Publications by authors named "Leticia Torres Dias"
Article Synopsis
- Conventional antigen presentation typically involves the processing of antigens by dendritic cells and their presentation on MHC class II molecules for CD4 T cell activation, while cross-presentation activates CD8 T cells through MHC class I using antigens acquired via phagocytosis.
- The study emphasizes the role of the CLEC9A receptor and synthetic hemozoin (sHz) in enhancing cross-presentation, particularly regarding its interaction with malaria pigment hemozoin (HZ) and associated pro-inflammatory responses.
- The research findings suggest that sHz can serve as an effective nanocarrier for antigens, potentially improving cross-presentation in dendritic cells and offering insights into new immunomodulatory strategies.
Unlabelled: a widespread parasite, has the ability to infect nearly any nucleated cell in warm-blooded vertebrates. It is estimated that around 2 billion people globally have been infected by this pathogen. Although most healthy individuals can effectively control parasite replication, certain parasites may evade the immune response, establishing cysts in the brain that are refractory to the immune system and resistant to available drugs.
View Article and Find Full Text PDFUnlabelled: a widespread parasite, has the ability to infect nearly any nucleated cell in warm-blooded vertebrates. It is estimated that around 2 billion people globally have been infected by this pathogen. Although most healthy individuals can effectively control parasite replication, certain parasites may evade the immune response, establishing cysts in the brain that are refractory to the immune system and resistance to available drugs.
View Article and Find Full Text PDF