Publications by authors named "Leticia Machado de Araujo"

Background: HIV infection is associated with various types of endothelial damage. Early and accurate diagnosis of endothelial dysfunction may help prevent adverse outcomes. For the first time, this cross-sectional study aims to investigate the effects of increased viral load on endothelial damage and nephrinuria in untreated people living with HIV.

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Acute kidney injury (AKI) is a common condition in hospitalized patients who often requires kidney support therapy (KST). However, predicting the need for KST in critically ill patients remains challenging. This study aimed to analyze endothelium-related biomarkers as predictors of KST need in critically ill patients with stage 2 AKI.

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Article Synopsis
  • The study aimed to assess how well vascular biomarkers can predict the need for hemodialysis in critically ill COVID-19 patients.
  • It involved 58 patients in the ICU, measuring biomarkers like VCAM-1 and angiopoietins upon admission.
  • The results indicated that VCAM-1 and the Ang-2/Ang-1 ratio were significant predictors for both dialysis necessity and mortality risk, with specific cutoff values helping to identify high-risk patients.
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