Assembly and antifungal effect of a new fluconazole-carrier nanosystem.

To assemble, characterize and assess the antifungal effects of a new fluconazole (FLZ)-carrier nanosystem. The nanosystem was prepared by loading FLZ on chitosan (CS)-coated iron oxide nanoparticles (IONPs). Antifungal effects were evaluated on planktonic cells (by minimum inhibitory concentration determination) and on biofilms (by quantification of cultivable cells, total biomass, metabolism and extracellular matrix) of and .