Health literacy of people with spinal cord injury: a systematic review.

Study Design: Systematic review.

Objective: To systematically review the evidence on health literacy (HL) of people diagnosed with spinal cord injury (SCI).

Methods: PubMed, Cochrane Library, Web of Science and Embase databases were used to identify studies published from 1974 to 2021.

Promising strategies for improving oral bioavailability of poor water-soluble drugs.

Introduction: Oral administration of poorly water-soluble drugs (PWSDs) is generally related to low bioavailability, leading to high drug doses, multiple side effects, and low patient compliance. Thus, different strategies have been developed to increase drug solubility and dissolution in the gastrointestinal tract, opening new venues for these drugs.

Areas Covered: This review outlines the current challenges in PWSD formulation development and the strategies to overcome the oral barriers and increase their solubility and bioavailability.