Clinical and Anthropological Analyses of a Case From 19th Century South Africa With a Confluence of Uncommon Cranial Pathological Conditions.

This study combines clinical and anthropological analyses to investigate the complex cranial pathology of a South African individual from the 19th century. The cranium was examined macroscopically and radiographically. Conducting a standard differential diagnosis was challenging given the complexity and uncommon nature of the pathology and required drawing on relatively sparse paleopathological and clinical case reports.

Bilateral hip dysplasia in a South African male: A case study from the 17-18th century.

Objective: To identify, critically analyse and describe severe bilateral skeletal pathology involving the ossa coxae of an individual from historic era Cape Town.

Materials: A single individual from the University of Cape Town's Human Skeletal Repository was analysed under research approval (HREC# 035/2021).

Methods: An osteobiography was constructed, radiocarbon dating and isotopic analyses were conducted.

Human migration in the eastern Tianshan Mountains between the 7th and 12th centuries.

Objective: Mid- to late-Holocene large-scale population migration profoundly impacted the interaction of ethnic groups and cultures across Eurasia, notably in Central Asia. However, due to a lack of thorough historical documents, distinctive burial items, and human remains, the process of population migration during this historical era in the area is still unclear. Using an interdisciplinary approach at the Lafuqueke (LFQK) cemetery, this study investigates the spatiotemporal processes and explores the factors that influenced human migration in the eastern Tianshan Mountains between the 7th and 12th centuries.

Metastatic cancer along ancient Silk Road: A possible case from Xinjiang (China).

Objective: Palaeopathological evidence of cancer, especially metastatic cancer, is rare in China. This paper describes and diagnoses a cranium with multiple lytic lesions recovered from the Sampula cemetery in Xinjiang, attempting to diagnose the type of disease that could have caused the pathological lesions observed.

Material: A cranium from an adult male (#00106) was recovered from the Sampula cemetery (dated to 55 BCE to 335 CE) located in the Luopu County, the Hotan River oasis on the southern edge of the Tarim Basin in southern Xinjiang.

Age-Related Changes in Orbits of Ancient Children from Zaghunluq Cemetery in Xinjiang, China.

Thirty-eight skull samples of ancient children were analyzed that were excavated from the Zaghunluq cemetery, which dates between 2600 and 1900 cal yr BP. The orbit features of children during age changes and growth spurt periods were explored by comparing the orbital height, orbital breadth, orbital area, orbital index, and other measurements among different age groups: 2 years, 3-5 years, 6-8 years, 9-11 years, and 12-15 years. The analysis showed significant differences in orbital breadth across the five age groups, while differences in orbital height, orbital area, and orbital index were not significant.

Diachronic changes in craniofacial morphology among the middle-late Holocene populations from Hehuang region, Northwest China.

Objectives: This study analyzes craniofacial shape variation in the Hehuang region of Northwest China within a population genetic framework, and takes a diachronic approach to explore the relationship betwee cultural discontinuity and biological continuity/discontinuity in the Hehuang region during the middle to late Holocene.

Materials And Methods: The sample comprises 76 adult skulls from five archaeological sites, ranging from 4,500 to 1,530 BP. 3D geometric morphometrics, multivariate statistics, quantitative evolutionary genetic and biodistance analyses were performed to study the diachronic variation in craniofacial morphology.

Generation of E3-deleted canine adenovirus type 2 expressing the Gc glycoprotein of Seoul virus by gene insertion or deletion of related terminal region sequences.

Seoul virus (SEOV) is one of the four hantaviruses known to cause haemorrhagic fever with renal syndrome. The medium genome segment encodes the Gn/Gc glycoproteins of SEOV, which form the major structural part of the virus envelope. Gc and/or Gn are the candidate antigens of hantavirus for induction of a highly immunogenic response for hantavirus vaccine.