Publications by authors named "Leteng Yang"
polymorphisms affect thyroid cancer risk in the Chinese Han population.
Expert Rev Mol Diagn
April 2024
Objectives: This study aimed to detect the correlation between polymorphisms and Thyroid cancer (TC) risk in the Chinese Han population.
Methods: We genotyped variants in 510 TC patients and 509 controls using Agena MassARRAY. We assessed the association between polymorphisms and TC susceptibility, with the significant results evaluated through FPRP analysis.
Genetic polymorphisms in CYP2B6 may be associated with lung cancer risk in the Chinese Han population.
Expert Rev Respir Med
December 2023
Article Synopsis
- The study investigated how variations in the CYP2B6 gene (specifically SNPs) relate to the risk of lung cancer in a Chinese population.
- Researchers analyzed 1,012 participants (507 lung cancer cases and 505 controls) using genetic testing and statistical methods to determine the association.
- The findings revealed specific SNPs that increase or decrease lung cancer risk, highlighting the importance of these genetic variations in understanding susceptibility to the disease.
Introduction: SMG5 is involved in tumor cell development and viewed as a potential target for immunotherapy. The purpose of this study was to systematically analyze the expression level, function, and prognostic value of SMG5 in pan-cancers.
Methods: Differential expression of SMG5 in normal and tumor tissues was analyzed using The Cancer Genome Atlas (TCGA) and the Genotype-Tissue Expression Database (GTEx) data.