An automatic recognition of the frontal sinus in x-ray images of skull.

In the present paper, a procedure is developed for fully automatic recognition of the frontal sinus in cranial radiographs. An X-ray image of a whole skull is required at the input of the procedure, which consists of three subsequent steps: the selection of a rectangular region of interest, containing the sinus; detection of the line of brow ridges; and fronto-nasal suture, detection of the borders of the frontal sinus. The recognition algorithm is based on a method of connectivity-preserving thresholding, introduced in the present study, and on watersheds from markers.

Detection of mitochondrial dysfunction by EPR technique in mouse model of dilated cardiomyopathy.

Tgalphaq44 mice with targeted overexpression of activated Galphaq protein in cardiomyocytes mimic many of the phenotypic characteristics of dilated cardiomyopathy in humans. However, it is not known whether the phenotype of Tgalphaq44 mice would also involve dysfunction of cardiac mitochondria. The aim of the present work was to examine changes in EPR signals of semiquinones and iron in Fe-S clusters, as compared to classical biochemical indices of mitochondrial function in hearts from Tgalphaq44 mice in relation to the progression of heart failure.

NO and PGI(2) in coronary endothelial dysfunction in transgenic mice with dilated cardiomyopathy.

Objective: The aim of the present work was to analyze coronary endothelial function in the transgenic mouse model of dilated cardiomyopathy (Tgalphaq*44 mice).

Methods: Coronary vasodilatation, both NO-dependent (induced by bradykinin) and PGI(2)-dependent (induced by acetylcholine), was assessed in the isolated hearts of Tgalphaq*44 and FVB mice. Cardiac function was analyzed in vivo (MRI).

Functional effects of eggs, naturally enriched with conjugated linoleic acid, on the blood lipid profile, development of atherosclerosis and composition of atherosclerotic plaque in apolipoprotein E and low-density lipoprotein receptor double-knockout mice (apoE/LDLR-/-).

The objective of this study was to evaluate potential anti-atherogenic properties of hen eggs enriched naturally with conjugated linoleic acid (CLA) isomers (cis-9, trans-11 and trans-10, cis-12). Eighteen apoE and LDL receptor double-knockout mice (apoE/LDLR- / - ), at the age of 4 months with pre-established atherosclerosis, were randomly assigned to three experimental groups (n 6) and fed AIN-93G-based diets for the next 2 months. The experimental diets were: AIN-93G+ CLA-free egg-yolk powder (control); AIN-93G+ CLA-free egg-yolk powder +0.

Does yeast shmooing mean a commitment to apoptosis?

Treatment of yeast Saccharomyces cerevisiae with alpha-pheromone has been reported to lead to massive apoptosis of cells finding no conjugation partner [Severin FF, Hyman AA. Pheromone induces programmed cell death in S. cerevisiae.

[Semiautomatic algorithm for tracing an outline of the endocardium in newborns].

Visual assessment of the endocardial outline is too subjective and the results do not provide enough support for reliable analysis. The main problem that hinders echocardiographic diagnosis in measurements of ventricular size and shape during subsequent cycles of cardiac function lies in difficulties in obtaining precise delineation of endocardial margins. A new, semiautomatic algorithm for tracing endocardial outlines of newborns that were detectable in echocardiographic images is presented.