Although the impact of tourism development on residents has received a lot of attention in the literature, the health impact of tourism has not been sufficiently addressed. Due to outbreaks of COVID-19, the importance of recognition of the negative health impact of tourism is relevant. Thus, the present study aims to identify the health impact of tourism through COVID-19 outbreaks considering residents' perspectives.
View Article and Find Full Text PDFThe purpose of this enquiry was to understand how gay men form and maintain their attitudes toward HIV transmission preventative behaviors. Autobiographical life histories of sixteen gay men showed that once they acquired knowledge of preventative behavior they consistently adhered to that behavior. They adhered because of fear of HIV infection and because they held a moral norm that obligated them to behave altruistically (Schwartz, 1977) to protect not only themselves, but also their sex partners, loved ones, and their positive self-evaluation.
View Article and Find Full Text PDFSocial media platforms are increasingly used to disseminate social marketing messages about mental health and wellbeing. This study presents a range of message appeals used in social media enabled mental health promotion and stigma reduction messages. Furthermore, it examines the relationship between the type of message appeals and audience engagement.
View Article and Find Full Text PDFThe impact of cancer involving the peripancreatic soft tissue (PST), irrespective of margin status, following a resection of pancreatic adenocarcinoma is not known. The purpose of this study is to determine such an impact on a cohort of patients. Data from 274 patients who underwent pancreatic surgery by our team between 1998 and 2012 was reviewed.
View Article and Find Full Text PDFThere are very few lung herniation cases described in literature. We present a case of a delayed lung herniation. In our case, the initial imaging was negative but patient developed a herniated lung during his hospital stay.
View Article and Find Full Text PDFIntroduction: Bilateral carotid artery dissection following blunt trauma is a rare but potentially lethal injury if not diagnosed early and treated.
Case Report: We report a collision patient who suffered bilateral asymptomatic carotid artery dissections. He also had multiple fractures of the pelvis and upper and lower extremities.
Abdominal aortic injury as a result of blunt trauma is a rare event and has been described in few children. A 6-year-old girl presented with acute bilateral lower extremity ischemia, and a triad of acute aortic occlusion, intra-abdominal visceral injury, and a lumbar chance fracture after sustaining a seat belt injury from a motor vehicle collision. An emergency aortic thromboendarterectomy and primary repair were performed.
View Article and Find Full Text PDFObjective: To examine and report surgical results from a contemporary experience of open abdominal aortic reconstruction in patients with chronic atherosclerotic abdominal aortic occlusion (CAAAO).
Methods: Between January 1999 through May 2010, 54 patients with CAAAO were identified and retrospectively reviewed. CAAAOs were categorized into infrarenal aortic occlusions (IRAOs) and juxtarenal aortic occlusions (JRAOs) based on superior extension of thrombus and requirement for supra-renal aortic clamping to repair.
Inflammatory aortic aneurysms are unusual vascular lesions and most commonly involve the infrarenal segment of the abdominal aorta. These complex aneurysms represent a challenge to the vascular surgeon and become even more difficult as the extent of the aneurysm and size of the inflammatory mass increase. Although well described, few cases of giant inflammatory aneurysms are reported.
View Article and Find Full Text PDFBackground: The expected outcome for hormone receptor-positive, node-negative patients should be favorable. However, some patients do develop metastatic disease and the mechanism for this observation is poorly understood. CXCR4 is a chemokine receptor that has been implicated to play a pivotal role in breast cancer growth and metastasis.
View Article and Find Full Text PDFCancer Epidemiol Biomarkers Prev
August 2009
Background: African American women have a higher breast cancer mortality rate than Caucasian women. To understand this difference, socioeconomic status (SES) needs to be controlled, which can be achieved by evaluating outcome within a population that is underinsured or low SES. We elected to examine the effect of race/ethnicity on outcome of patients with operable breast cancer by evaluating outcome in a population with low SES and similar access to care.
View Article and Find Full Text PDFIntroduction: Basal-like tumors or triple negative breast cancers are those that lack hormone-receptor and HER-2 expressions. They are considered to be aggressive tumors, and molecular mechanism to account for this is poorly understood. CXCR4 is a chemokine receptor that has been linked to breast cancer invasion and metastasis.
View Article and Find Full Text PDFPurpose Patients with locally advanced breast cancer (LABC) have a poor outcome. A molecular predictor to identify at-risk patients is sorely needed. CXCR4 is a chemokine receptor that has been linked to breast cancer invasion and metastasis.
View Article and Find Full Text PDFBackground: Tousled-like kinase 1B (TLK1B), a mammalian threonine kinase, facilitates the repair of DNA breaks. Eukaryotic initiation factor 4E (eIF4E) overexpression leads to the upregulation of TLK1B. Doxorubicin, commonly used in the adjuvant setting for breast cancer, causes DNA breaks.
View Article and Find Full Text PDFGastrointestinal stromal tumors, commonly known as GISTs, are non-epithelial gastrointestinal neoplasms seen with increasing frequency in clinical practice. These tumors were formerly classified as leiomyoblastomas or leiomyosarcomas. Recent advances in immunohistochemistry have identified gastrointestinal stromal tumors as a unique entity.
View Article and Find Full Text PDFBackground: The role of whole-body fluorine-18-FDG positron emission tomography (FDG-PET) as an adjunct localize recurrence in stages II and III breast cancer patients who present with clinical suspicion for recurrence is not well established. We report our experience in such a patient population.
Methods: A retrospective review of all patients with stages II and III breast cancer who had a whole-body FDG-PET scan was performed.
Objective: In a prospective trial, to determine if eIF4E overexpression in breast cancer specimens is correlated with VEGF elevation, increased tumor microvessel density (MVD) counts, and a worse clinical outcome irrespective of nodal status.
Summary And Background Data: In vitro, the overexpression of eukaryotic initiation factor 4E (eIF4E) up-regulates the translation of mRNAs with long 5'-untranslated regions (5'-UTRs). One such gene product is the vascular endothelial growth factor (VEGF).
The following are excerpts from testimony given in favor of House Bill 849 before the Ways and Means Committee of the Louisiana House of Representatives on June 7, 2005. The bill asked for funding of a time sensitive illness and Homeland Security Emergency System for the State of Louisiana. Bill 849 was defeated by a vote of 9 - 2 in committee but subsequently rudimentary funding was secured in the joint conference committee of the House and Senate by Senate President Dr.
View Article and Find Full Text PDFAn incidental finding of focal thyroid uptake (thyroid incidentaloma) from an 18F-fluorodeoxyglucose positron emission tomography (PET) positron presents a diagnostic challenge. We evaluated the incidence of thyroid incidentaloma identified by PET scans and the likelihood of malignancy associated with this finding. Records from all patients from January 1, 2000 to November 30, 2003 who had focal thyroid uptake without any history of thyroid disease were culled.
View Article and Find Full Text PDFObjective: A previous study of patients with stage I to III breast cancer showed that those patients whose tumors were in the highest tertile of eIF4E overexpression experienced a higher risk for recurrence. This study was designed to determine whether high eIF4E overexpression predicts cancer recurrence independent of nodal status by specifically targeting patients with node-positive disease.
Methods: The prospective trial was designed to accrue 168 patients with node-positive breast cancer to detect a 2.
Histoplasmosis is a rare, but important, disease process in patients with the acquired immune deficiency syndrome (AIDS). Initially reported in this patient population in 1982, over 100 cases of histoplasmosis have been reported throughout the United States. Most of these patients present with disseminated disease.
View Article and Find Full Text PDFAmong women with advanced breast cancer, African Americans are thought to have a higher mortality rate than Caucasian. A number of factors, including intrinsic tumor biology, have been postulated for this survival difference. If similar treatment were offered, and actually completed, is there a survival difference? The objectives of this study were to determine 1) if the treatment regimens offered to African Americans and Caucasian were the same, 2) when treatment was offered, was compliance a factor, and 3) if the patients were compliant, was the outcome different? A retrospective review of 72 charts of patients with advanced stage breast cancer from 1988-present at our institution and an affiliated hospital was performed.
View Article and Find Full Text PDFRetroperitoneal soft-tissue sarcoma is a rare and unusual entity, comprising about 0.1% of all tumors. Optimal outcome depends on a thorough understanding of its clinical behavior.
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