Publications by authors named "Lester J Fahrner"

Objective: The purposes of this article are to review the treatment options for late-stage biventricular heart failure, discuss the clinical indications for total artificial heart (TAH) implantation, illustrate the expected imaging findings after uncomplicated TAH implantation, and highlight the radiologic findings of common and uncommon complications associated with TAH implantation through case examples.

Conclusion: TAH implantation is an effective therapeutic option for the treatment of patients with end-stage biventricular heart failure. The duration of implantation varies depending on a particular patient's medical condition and the eventual availability of a human heart for orthotopic transplantation.

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Mohs' micrographic surgery is a surgical technique developed for removal of mucocutaneous malignancies. The surgeon integrates the responsibilities of surgery, specimen orientation and preparation, and microscopic interpretation to determine tumor-free margins. It has the lowest recurrence rate of all surgical techniques while conserving the most tumor-free skin.

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A significant amount of the data collected by cell biologists and tissue engineers relies on invasive imaging techniques to visualize dynamic structural and functional properties in engineered tissues. We report the use of optical coherence tomography and the comparative use of confocal microscopy to nondestructively and noninvasively monitor the structural and functional characteristics of three-dimensional engineered tissues over time. The engineered tissue model is composed of chitosan scaffolds and fibroblasts transfected with vinculin fused to green fluorescent protein.

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