Role of mothers in preventing tuberculosis in children: A scoping review.

Tuberculosis (TB) remains a significant global health challenge, especially for children. The aim of this scoping review was to investigate the role of mothers in preventing childhood TB transmission and highlight effective strategies and associated barriers. A systematic literature search was conducted using PubMed, Web of Science, and Scopus, covering articles up to January 17, 2024.

Systemic allopurinol administration reduces malondialdehyde, interleukin 6, tumor necrosis factor α, and increases vascular endothelial growth factor in random flap Wistar rats exposed to nicotine.

Introduction: Smoking poses a risk to flap viability, with nicotine being a major contributor to the formation of free radicals. Allopurinol, known for its antioxidant properties, has been shown to enhance tissue survival in ischemic conditions by reducing the production of reactive oxygen species (ROS). This study aims to assess the impact of allopurinol on the viability and success of skin flaps in Wistar rats exposed to nicotine.

Predischarge Peak Atrial Longitudinal Strain and Plasma N-terminal Pro-hormone Brain Natriuretic Peptide as a Predictor of Short-term Rehospitalization and Cardiovascular Mortality in Patients with Acute Heart Failure.

Context: The postacute heart failure (AHF) rehospitalization rate is attributed to persistent hemodynamic congestion despite clinical improvement. Peak atrial longitudinal strain (PALS), utilizing speckle tracking echocardiography technology, shows potential in post-AHF prognosis. Meanwhile, N-terminal pro-hormone brain natriuretic peptide (NT-proBNP) remains a known biomarker of intracardiac congestion.

A clinical and novel dermoscopic investigation of combined peels as a hand aging treatment.

Background: The hands are one of the areas where skin aging is most noticeable, alongside the face, but limited studies used dermoscopic evaluation on hand aging. The Dermoscopy Photoaging Scale (DPAS) is frequently used to assess face aging but is never used for hand aging. Treating skin aging using chemical peeling is a commonly used method to rejuvenate the skin on the hands, as it is relatively affordable.

Infringement of clinical pharmacist's authority.

Clinical pharmacists are healthcare practitioners who have advanced education and training in comprehensive medication management. Clinical pharmacists work with other members of the healthcare team to manage particular medications or disease states. Even though clinical pharmacists are members of healthcare teams, there are still many cases of challenge in the interprofessional relationship with other healthcare team members, especially related to drug management.

Aberrant SOX10 and RET expressions in patients with Hirschsprung disease.

Background: HSCR is a complex genetic disorder characterized by the absence of ganglion cells in the intestine, leading to a functional obstruction. It is due to a disruption of complex signaling pathways within the gene regulatory network (GRN) during the development of the enteric nervous system (ENS), including SRY-Box Transcription Factor 10 (SOX10) and REarranged during Transfection (RET). This study evaluated the expressions of SOX10 and RET in HSCR patients in Indonesia.

Factors affecting the health-related quality of life of children with cerebral palsy in Indonesia: a cross-sectional study.

Purpose: Children with cerebral palsy (CP) and their parents experience various problems that can affect their quality of life. This study examined factors affecting the quality of life of children with CP.

Methods: A cross-sectional study was conducted in Yogyakarta, Indonesia, from January to August 2019.

Results of professional interventions to improve medication adherence based on health beliefs and important determinants of tuberculosis medication: a systematic review.

Objective: Nonadherence to tuberculosis (pulmonary TB) medication poses a serious threat to the increase in new cases, prevention of transmission, and control of pulmonary TB. The health behavior of patients with pulmonary TB regarding medication adherence is an extremely important issue to investigate. This review aimed to identify the available literature on professional interventions and important determinants for improving adherence to pulmonary TB medication based on a health belief model (HBM).

γδ T cells control murine skin inflammation and subcutaneous adipose wasting during chronic Trypanosoma brucei infection.

African trypanosomes colonise the skin to ensure parasite transmission. However, how the skin responds to trypanosome infection remains unresolved. Here, we investigate the local immune response of the skin in a murine model of infection using spatial and single cell transcriptomics.

Safe-by-Design Antibacterial Peroxide-Substituted Biomimetic Apatites: Proof of Concept in Tropical Dentistry.

Bone infections are a key health challenge with dramatic consequences for affected patients. In dentistry, periodontitis is a medically compromised condition for efficient dental care and bone grafting, the success of which depends on whether the surgical site is infected or not. Present treatments involve antibiotics associated with massive bacterial resistance effects, urging for the development of alternative antibacterial strategies.

Bioactive Compounds in Garlic () and Black Garlic as Antigout Agents, Using Computer Simulation.

Uric acid, which causes gout, is the end product of purine catabolism, synthesized by xanthine oxidase, guanine deaminase, adenine deaminase, purine nucleoside phosphorylase, and 5-nucleotidase II. Garlic contains bioactive compounds that have potential as antigout agents. Garlic fermentation to black garlic changes its components, which may affect its beneficial potential.

How do elderly people with malnutrition and their families perceive collaborative practice in primary care? A phenomenological study.

As a frequent and serious problem in elderly people, malnutrition is a complex health issue. It requires comprehensive care through interprofessional collaborative practice (IPCP) engaging five health professionals in primary care consisting of a physician, dentist, nurse, dietitian and pharmacist. In Indonesia, the usual care involves monthly health screening in community programmes named The current study aimed to explore perceptions of elderly people with malnutrition and their families' experiences with interprofessional teams compared with usual care in primary care.

A large cluster of human infections of in Bali, Indonesia.

A cluster of 18 inpatients and 21 outpatients with a major complaint of meningitis and a history of sharing traditional delicacies of raw pork and pig blood in a village festival led to the suspicion of meningitis in Sibang Kaja Village, Badung, Bali, Indonesia. We conducted an investigation and case finding to prevent human fatalities. Demography and laboratory examinations of the inpatients were recorded.

FITRI's four steps in developing primary health cares' interprofessional collaborative: an intervention for fostering IPCP competencies.

It is important to fill the gaps in collaborative practice due to the lack of the healthcare professionals' ability to work in collaboration with other disciplines. However, the current team training does not routinely address this important issue. This study aimed to identify how interactive interprofessional collaborative practice (IPCP) learning materials in a virtual course and community implementation called can be used in primary healthcare settings to address IPCP competencies of healthcare providers.

Control of cambium initiation and activity in Arabidopsis by the transcriptional regulator AHL15.

Plant secondary growth, which is the basis of wood formation, includes the production of secondary xylem, which is derived from meristematic cambium cells embedded in vascular tissue. Here, we identified an important role for the Arabidopsis thaliana (Arabidopsis) AT-HOOK MOTIF CONTAINING NUCLEAR LOCALIZED 15 (AHL15) transcriptional regulator in controlling vascular cambium activity. The limited secondary xylem development in inflorescence stems of herbaceous Arabidopsis plants was significantly reduced in ahl15 loss-of-function mutants, whereas constitutive or vascular meristem-specific AHL15 overexpression produced woody inflorescence stems.

Disease-Associated Systemic Complications in Childhood Nephrotic Syndrome: A Systematic Review.

Introduction: Nephrotic syndrome (NS) is one of the most common childhood kidney diseases. During the active phase, the disease pathogenesis affects various biological functions linked to loss of proteins negatively, which can result in systemic complications. Complications of childhood NS are divided into two categories: disease-associated complications and drug-associated complications.

The association between therapeutic plasma exchange and the risk of mortality among patients critically ill with COVID-19: a meta-analysis.

Cytokine storm has been widely known to contribute to the development of the critical condition in patients with coronavirus disease 2019 (COVID-19), and studies had been conducted to assess the potential aspect of cytokine storm elimination by performing therapeutic plasma exchange (TPE). However, contradictory findings were observed. The objective of this study was to assess the association between TPE and the reduction of mortality of critically ill COVID-19 patients.

Artificial Intelligence in Medicine: A Multinational Multi-Center Survey on the Medical and Dental Students' Perception.

The emerging field of artificial intelligence (AI) will probably affect the practice for the next generation of doctors. However, the students' views on AI have not been largely investigated. An anonymous electronic survey on AI was designed for medical and dental students to explore: (1) sources of information about AI, (2) AI applications and concerns, (3) AI status as a topic in medicine, and (4) students' feelings and attitudes.

Physicochemical Properties of Mesoporous Organo-Silica Xerogels Fabricated through Organo Catalyst.

The physicochemical properties of organo-silica xerogels derived from organo catalyst were pervasively investigated, including the effect of one-step catalyst (citric acid) and two-step catalyst (acid-base), and also to observe the effect of sol pH of organo-silica xerogel toward the structure and deconvolution characteristic. The organo-silica xerogels were characterized by FTIR, TGA and nitrogen sorption to obtain the physicochemical properties. The silica sol-gel method was applied to processed materials by employing TEOS (tetraethyl orthosilicate) as the main precursor.

Effectiveness of collaboration in older adults: do interprofessional teams improve nutritional status more compared to usual care?

Background: Ageing is accompanied by many changes that make it more difficult for nutritional needs to be met. Management of malnutrition in older adults requires collaboration among multiple clinical disciplines.

Objective: This study aimed to determine the effectiveness of interprofessional collaboration and practice (IPCP) implementation for older adults with malnutrition compared to usual care.

Nasopharyngeal carriage and antimicrobial susceptibility profile of among patients infected with HIV in Jakarta, Indonesia.

In this study, the prevalence of nasopharyngeal carriage and the antimicrobial susceptibility profile of were investigated in children and adults with HIV infection in Jakarta, Indonesia. Thirty-four isolates were identified in the children (=16/90; 18%) and adults (=18/200; 9%) infected with HIV. All isolates were nontypeable and were less susceptible to ampicillin (62%) and trimethoprim/sulfamethoxazole (41%).

Medicinal Effect, Bioactivity Prediction, and Pharmaceutical Formulation of L.: A Review.

Goat weed ( L.), or bandotan in Indonesia, is an herbaceous plant that broadly grows up in both subtropical as well as tropical areas. This herb contains many phytoconstituents which have many benefits in different aspects.