Publications by authors named "Leslie K Mihalov"
Objective: This prospective, longitudinal cohort study examined the trajectory, classification, and features of posttraumatic headache after pediatric mild traumatic brain injury.
Methods: Children ( = 213; ages 8.00 to 16.
Article Synopsis
- * Out of 588 eligible children approached in emergency departments, 315 consented to participate, with higher consent rates among Black and multi-racial children compared to white children.
- * Retention rates for follow-up assessments showed that while many participants returned, Black children had significantly lower return rates compared to multi-racial and white participants, indicating a need for strategies to improve equity in clinical research participation.
Objective: The study sought to present normative and psychometric data and reliable change formulas for the Health and Behavior Inventory (HBI), a postconcussive symptom rating scale embedded in the Child Sport Concussion Assessment Tool 5th edition (Child SCAT5).
Design: Prospective cohort study with longitudinal follow-up.
Setting: Pediatric emergency departments (EDs).
This study is the first to examine cognitive outcomes after pediatric mild TBI using the National Institutes of Health Toolbox Cognition Battery (NIHTB-CB), a computerized cognitive test battery. The NIHTB-CB includes two complex measures of attention and executive function that allow differentiation of accuracy and response speed. We compared performance on the NIHTB-CB among children 8-16 years of age with mild TBI ( = 143) versus children with orthopedic injuries (OIs; = 74) recruited in emergency departments and followed for 6 months post-injury.
View Article and Find Full Text PDFSex differences after concussion have been studied largely in high school and college athletes, often without reference to comparison groups without concussion. This study sought to evaluate sex differences in outcomes among all children and adolescents presenting to the Emergency Department (ED) for either mild traumatic brain injury (TBI) or orthopedic injury (OI), regardless of mechanism of injury. The study involved a concurrent cohort, prospective study design with longitudinal follow-up.
View Article and Find Full Text PDFArticle Synopsis
- * Results showed significant differences in left parietal cortical thickness between TBI and OI groups, with TBI group exhibiting thicker cortices immediately after the injury; however, no significant differences were found at 3 or 6 months post-injury.
- * The study highlighted that certain brain regions' cortical thickness (like right frontal and right cingulum) could predict post-acute and chronic symptoms in children, indicating the complexities in understanding outcomes from mild TBI.
Article Synopsis
- Mild traumatic brain injury (TBI) is a widespread issue impacting many children each year, often resulting in subtle brain changes that make detection tough.
- The study compared white matter microstructure in children with mild TBI to those with mild orthopedic injuries using diffusion tensor imaging (DTI) to predict symptoms over time.
- Results showed no significant differences in white matter tracts between groups, but certain DTI metrics, particularly from the corpus callosum, did correlate with post-injury symptoms over 3 and 6 months.
Age- and sex-related effects in children with mild traumatic brain injury on diffusion magnetic resonance imaging properties: A comparison of voxelwise and tractography methods.
J Neurosci Res
April 2018
Although there are several techniques to analyze diffusion-weighted imaging, any technique must be sufficiently sensitive to detect clinical abnormalities. This is especially critical in disorders like mild traumatic brain injury (mTBI), where pathology is likely to be subtle. mTBI represents a major public health concern, especially for youth under 15 years of age.
View Article and Find Full Text PDFObjectives: The Pediatric Early Warning Score (PEWS) systems were developed to provide a reproducible assessment of a child's clinical status while hospitalized. Most studies investigating the PEWS evaluate its usefulness in the inpatient setting. Limited studies evaluate the effectiveness and integration of PEWS in the pediatric emergency department (ED).
View Article and Find Full Text PDF