Influence of computer-aided detection false-positives on reader performance and diagnostic confidence for CT colonography.

Objective: The objective of our study was to investigate whether an increasing number of computer-aided detection (CAD) false-positives decreases reader sensitivity, specificity, and confidence for nonexpert readers of CT colonography (CTC).

Materials And Methods: Fifty CTC data sets (29 men; mean age, 65 years), 25 of which contained 35 polyps > or = 5 mm, were selected in which CAD had 100% polyp sensitivity at two sphericity settings (0 and 75) but differed in the number of false-positives. The data sets were read by five readers twice: once at each sphericity setting.

CT colonography: effect of colonic distension on polyp measurement accuracy and agreement-in vitro study.

Rational And Objectives: To investigate the effect of colonic distension on polyp measurement accuracy and reader agreement.

Materials And Methods: Institutional review board permission was obtained. A sealed colectomy specimen from a patient with familial adenomatous polyposis was scanned using a four-detector-row computed tomography (CT) after half and full air distension.

Polyp detection with CT colonography: primary 3D endoluminal analysis versus primary 2D transverse analysis with computer-assisted reader software.

Purpose: To retrospectively compare primary three-dimensional (3D) endoluminal analysis with primary two-dimensional (2D) transverse analysis supplemented by computer-assisted reader (CAR) software for computed tomographic (CT) polyp detection and reader reporting times.

Materials And Methods: Ethical permission and patient consent were obtained from all donor institutions for use of CT colonography data sets. Twenty CT colonography data sets from 14 men (median age, 61 years; age range, 52-78 years) with 48 endoscopically proved polyps were selected.