Publications by authors named "Leslie Guzene"
Article Synopsis
- The study investigates the variability in delineation of target volumes and organs at risk in radiation therapy, highlighting the uncertainty and lack of standardized methods in interobserver variability (IOV) studies.
- A systematic review of 66 published IOV studies from 2018-2021 reveals issues like the independent study of organs at risk, absence of defined gold standards, and inconsistent results in key metrics like the Dice similarity coefficient.
- To improve future IOV studies, the authors recommend standardizing methodologies and clearly defining measurements and reference standards to ensure better reproducibility and reliability of results.
Several reports have suggested that radiotherapy after reconstructive surgery for head and neck cancer (HNC), could have deleterious effects on the flaps with respect to functional outcomes. To predict and prevent toxicities, flap delineation should be accurate and reproducible. The objective of the present study was to evaluate the interobserver variability of frequent types of flaps used in HNC, based on the recent GORTEC atlas.
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