Pathophysiology and current management of burn injury.

Purpose: To provide the physician and registered professional nurse with an overview of the pathophysiology and current management of burn injuries.

Target Audience: This continuing education activity is intended for physicians and nurses with an interest in learning about evidence-based prevention and management of burn wounds.

Objectives: After reading the article and taking the test, the participant should be able to: (1) Explain the pathophysiology of skin function.

Oxandrolone induced lean mass gain during recovery from severe burns is maintained after discontinuation of the anabolic steroid.

Weight loss and lean mass loss from burn induced catabolism can be more rapidly restored when the anabolic steroid oxandrolone is added to optimum nutrition compared to nutrition alone. Our purpose in this study was to determine whether the regained lean body mass (LBM) is retained 6 months after stopping oxandrolone. Forty-five severe burn patients, entering the recovery phase were randomized into a nutrition group alone or with the addition of oxandrolone, 20mg per day upon admission to the acute burn rehabilitation (RH) unit.

The rate of re-epithelialization across meshed skin grafts is increased with exposure to silver.

Unlabelled: The objective in this study was to determine whether exposure to pure silver increases the rate of re-epithelialization across a partial thickness wound. A meshed skin graft, placed on an excised burn wound was used as a healing model.

Methods: The rate of meshed skin graft epithelial closure on an exposed burn using a moist healing environment was shown.