Publications by authors named "Leslie C Alvarez"

Article Synopsis
  • The study focused on Aedes aegypti, the main mosquito responsible for spreading diseases like dengue and Zika, revealing that these populations in Mexico have developed high levels of resistance to commonly used insecticides (pyrethroids).
  • Results showed that all tested populations were resistant to various pyrethroids, with specific genetic mutations (kdr mutations V1016I and F1534C) linked to the observed resistance levels in bioassays.
  • The findings emphasize the importance of monitoring genetic resistance alongside traditional insecticide testing to effectively manage and control mosquito populations and the diseases they transmit.
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Background: The V1016I and F1534C mutations in the voltage-gated sodium channel gene have been associated with resistance to pyrethroids and DDT in Aedes aegypti mosquitoes. A study was carried out to determine the frequency of I1016 and C1534 by real-time PCR in five natural populations of Ae. aegypti in Venezuela during 2008, 2010 and 2012, as well as in a strain selected with 0.

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Background: Temephos is an insecticide widely used in Venezuela to control the proliferation of the larvae of Aedes aegypti (L.), the principal vector of dengue virus. The aim of this study was to identify the susceptibility to temephos of Ae.

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Resistance to the insecticides deltamethrin and malathion and the enzymes associated with metabolic resistance mechanisms were determined in four field populations of Aedes aegypti (L.) from western Venezuela during 2008 and 2010 using the bottle assay and the microplate biochemical techniques. For deltamethrin, mortality rates after 1 h exposure and after a 24-h recovery period were determined to calculate the 50% knock-downconcentration (KC50) and the lethal concentration (LC50), respectively.

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