Publications by authors named "Lesbros F"

The authors report five observations of endometrial stromal nodules. These nodules are composed of cells identical to those of the endometrial stroma. They constitute the benign form of endometrial stromal tumors.

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This report describes the histologic, immunocytochemical, and ultrastructural study of a multihormonal carcinoid tumor of the pancreas, secreting a growth hormone releasing factor (GRF) which provoked acromegaly. The patient presented a nonfamilial multiple endocrine neoplasia, type 1. The absence of radiologic signs of a pituitary adenoma in conjunction with elevated plasma levels of pancreatic polypeptide, glucagon, somatostatin, as well as growth hormone (GH), led to the discovery of the tumor.

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Morphometry was applied to quantitate characteristic microscopical features of the removed non invasive papillary bladder tumours in 60 patients and of the normal urothelium in 13 cases. The measurements of nuclear areas were made on routine HES section with a microscopic digitiser (ASM-Leitz). There was a significant difference, concerning the average nuclear area, between normal urothelium and bladder tumours and also a correlation between the number of relapses at two years and this parameter.

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A patient is described in whom a segment of colon used to construct an artificial vagina was therefore removed from intestinal continuity and was affected by typical idiopathic ulcerative colitis. The onset of disease was simultaneous in this loop of colon and in the rectum. There was no evidence of local infection.

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The authors report on two cases of severe ulcerated forms of acute colitis, successfully treated by total colectomy. Laboratory and X-ray investigations, as well as pathological examination of the removed section did not provide a definite etiopathologic classification. They voice the hypothesis of an infectious involvement and discuss the diagnostic and therapeutic problems evoked by these ulcerated forms of acute colitis.

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The pathologic features, the terminology, the etiolgoy, and the causal relations of benign tumours of the liver associated with the use of oral contraceptives were reviewed during a study on six new cases. According to the literature the following points are emphasized: these tumours can be divided into two distinctive conditions, they are commonly called focal nodular hyperplasia and liver cell adenoma, whereas the name hamartoma seems rarely appropriated, they occur without any use of oral contraceptive, but this practice is probably responsible for their increasing number.

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A nephroblastoma occurred in the evolution of a case of Beckwith's syndrome. This rare association is not fortuitous. The bifocal character of the tumor is noted for the first time in the Beckwith's syndrome; however, it has already been observed in other conditions, which are known to promote the development of nephroblastomas.

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The authors present the results of a quantitative study of carcinoma-in-situ and occult invasive cancers of the cervix. 40 separate carcinomata in-situ were measured and the limits of their topography precisely defined with reference to the external os on the one hand and the "last gland" on the other. It is known that this gland is situated at the site of the original junction between the cylindrical and pavement epithelia.

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