Persistence, integration into host genome, germ line transmission and expression of foreign genes microinjected into cytoplasm of fertilized rainbow trout eggs has been examined. Foreign DNA persisted as large random concatenates in approximately 50% of 6 to 12 month-old trout and exhibited a mosaic pattern between tissues. In some cases, free concatenates were observed indicating that extrachromosomal replication occurred in trout.
View Article and Find Full Text PDFArch Mal Coeur Vaiss
December 1983
This prospective study was initiated in March 1981 and all results were compared with arteriography. The investigations were carried out with a real time Toshiba SAL 20 equipped with a 5 MHz transducer and a DUD 400 continuous Doppler ultrasonogram with a 4 MHz transducer. All patients were referred to us from the neurological and cardiac departments of our hospital.
View Article and Find Full Text PDFBiochim Biophys Acta
March 1982
Prostaglandin synthesis in aortic smooth muscle cells originating from healthy an atherosclerotic rabbits was studied by incubating [14C]arachidonic acid with intact confluent cells and cell homogenates. In spite of a reduced 6-keto prostaglandin F1 alpha formation, no potentiating effect on the prostaglandin E2 generation occurred. Indeed, both cyclooxygenase and prostaglandin I2 synthetase activities appear to be reduced.
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