Ethics, One Health approaches, and SDGs: conference lessons for an emerging field.

One Health ethics is an emerging field that has gained traction since its origin in approximately 2015. This article builds upon the insights shared during a panel discussion on at the 28th Annual International Sustainable Development Research Society Conference. The conference, themed aimed to advance and expand recent knowledge in the field.

Anaerobic spp. degrade sulfoquinovose via a bifurcated 6-deoxy-6-sulfofructose transketolase/transaldolase pathway to both C- and C-sulfonate intermediates.

Plant-produced sulfoquinovose (SQ, 6-deoxy-6-sulfoglucose) is one of the most abundant sulfur-containing compounds in nature and its bacterial degradation plays an important role in the biogeochemical sulfur and carbon cycles and in all habitats where SQ is produced and degraded, particularly in gut microbiomes. Here, we report the enrichment and characterization of a strictly anaerobic SQ-degrading bacterial consortium that produces the C-sulfonate isethionate (ISE) as the major product but also the C-sulfonate 2,3-dihydroxypropanesulfonate (DHPS), with concomitant production of acetate and hydrogen (H). In the second step, the ISE was degraded completely to hydrogen sulfide (HS) when an additional electron donor (external H) was supplied to the consortium.

Donor-free 9-aluminafluorenes: molecular structures and reactivity.

Aluminum-doped polycyclic aromatic hydrocarbons (PAHs) are underexplored despite the broad applications of boron-containing PAHs in areas such as catalysis and optoelectronics. We disclose the donor-free, sterically unprotected 9-methyl-9-aluminafluorene (Me-AlFlu; 2), synthesized by heating a 9,9-dimethyl-9-stannafluorene and AlMe in hexanes. The compound is a dimer, (2), with -positioned Al substituents in the solid state.

A novel coded healing abutment for a simplified digital workflow: A retrospective clinical study on 103 patients with a one year follow-up.

Objectives: To present the clinical results obtained using a novel coded healing abutment (CHA).

Methods: We evaluated 103 patients with fixed implant-supported zirconia restorations (90 single crowns, 26 partial dentures, and 6 full arches) manufactured via computer-aided-design/computer-assisted-manufacturing and starting from the point of intraoral scans of novel CHAs (i-Physio®, LYRA-ETK, Sallanches, France). Patients were followed for one year.

Effects of the intraoral scanner and implant library on the trueness of digital impressions in the full-arch implant scan: A comparative in vitro study.

Objective: To evaluate the effect of intraoral scanners (IOSs) and implant libraries (ILs) on the trueness of digital impressions for the fabrication of implant-supported full-arch (FA) prostheses.

Methods: A stone cast of an edentulous maxilla with 6 implant analogues and cylindrical scanbodies (IPD ProCam®, Matarò, Barcelona, Spain) was probed using a coordinate measuring machine to capture a reference model (RM). The cast was mounted on a mannequin and scanned with 3 different IOSs (iTERO Element 5D Plus®, Align Technologies, San José, CA, USA; IS 3800®, Dexis, Quackertown, PN, USA; and i-700®, Medit, Seoul, South Korea).

Adjusting the Number of Functional Groups in Vicinal Bis(trichlorosilylated) Benzenes.

Organo(chloro)silanes are essential chemicals, but the synthesis of compounds of the formula RSiCl with defined values of n is usually laborious. Herein, we first disclose that a [4+2]-cycloaddition between readily available ClSiC≡CSiCl and selected dienes provides facile access to vicinal bis(trichlorosilylated) benzenes and bicyclo[2.2.

Artificial intelligence and mixed reality for dental implant planning: A technical note.

Aim: The aim of this work is to present a new protocol for implant surgical planning which involves the combined use of artificial intelligence (AI) and mixed reality (MR).

Methods: This protocol involves the acquisition of three-dimensional (3D) patient data through intraoral scanning (IOS) and cone beam computed tomography (CBCT). These data are loaded into AI software which automatically segments and aligns the patient's 3D models.

3D-printed short-span hybrid composite implant-supported restorations fabricated through tilting stereolithography: A retrospective clinical study on 85 patients with 1 year of follow-up.

Purpose: To report the clinical results obtained with fixed short-span (single crowns [SCs] and fixed partial prostheses [FPPs]) implant-supported hybrid composite restorations fabricated through tilting stereolithography (TSLA).

Methods: This retrospective clinical study included 85 patients who had been restored with 95 fixed short-span implant-supported hybrid composite (Irix Max®, DWS Systems) restorations (70 SCs and 25 FPPs up to three units) fabricated with TSLA. The full-digital model-free workflow was based on intraoral implant scanning, computer-assisted design (CAD) and 3D printing using TSLA (Dfab®, DWS Systems).

Borylation and rearrangement reactions of azasilaanthracenes to afford B,N-doped nanographenes.

An air-stable B,N-containing dibenzobisanthene (8) was prepared in 29% yield by heating a 1,3,5-tri(azasilaanthryl)benzene (5) with BBr (180 °C). Under these conditions, the reaction does not stop after threefold SiMe/BBr exchange but proceeds further two rearrangement and two intramolecular C-H borylation steps. Some mechanistic details were unveiled by using smaller model systems and applying lower reaction temperatures.

Accuracy of implant placement using a mixed reality-based dynamic navigation system versus static computer-assisted and freehand surgery: An in Vitro study.

Purpose: This in vitro study aimed to compare the accuracy of dental implant placement in partially edentulous maxillary models using a mixed reality-based dynamic navigation (MR-DN) system to conventional static computer-assisted implant surgery (s-CAIS) and a freehand (FH) method.

Methods: Forty-five partially edentulous models (with teeth missing in positions #15, #16 and #25) were assigned to three groups (15 per group). The same experienced operator performed the model surgeries using an MR-DN system (group 1), s-CAIS (group 2) and FH (group 3).

Tetramerization of BEB-Doped Phenalenyls to Obtain (BE)-[16]Annulenes (E = N, O).

Two (BE)-[16]annulenes were prepared and fully characterized by experimental and quantum-chemical means (, E = N; , E = O). The 1,8-naphthalenediyl-bridged diborane(6) served as their common starting material, which was treated with [Al(NH)]Cl to form (91% yield) or with 1,8-naphthalenediboronic acid anhydride to form (93% yield). As a result, the heteroannulenes and are supported by four aromatic "clamps" and may also be viewed as NH- or O-bridged cyclic tetramers of BNB- or BOB-doped phenalenyls.

Impaired long-range excitatory time scale predicts abnormal neural oscillations and cognitive deficits in Alzheimer's disease.

Background: Alzheimer's disease (AD) is the most common form of dementia, progressively impairing cognitive abilities. While neuroimaging studies have revealed functional abnormalities in AD, how these relate to aberrant neuronal circuit mechanisms remains unclear. Using magnetoencephalography imaging we documented abnormal local neural synchrony patterns in patients with AD.

NBN- and BNB-Phenalenyls: the Yin and Yang of Heteroatom-doped π Systems.

NBN- and BNB-doped phenalenyls are isoelectronic to phenalenyl anions and cations, respectively. They represent a pair of complementary molecules that have essentially identical structures but opposite properties as electron donors and acceptors. The NBN-phenalenyls 1-4 considered here were prepared from N,N'-dimethyl-1,8-diaminonaphthalene and readily available boron-containing building blocks (i.

Green-Emitting Extended B,N-Doped Polycyclic Aromatic Hydrocarbon with Multiple Resonance Structure.

An air-stable B,N-PAH (; nine annulated six-membered rings) was synthesized from 1-X-2,6-di(azasilaanthryl)benzenes (X = Cl, I) via lithiation/borylation, electrophilic aromatic borylation, and Si/B exchange. The heteroatom distribution in meets the requirements for multiple resonance thermally activated delayed fluorescence (MR-TADF). Indeed, emits green light (λ = 523 nm; Φ = 85%; CHCl) with a small fwhm of 0.

Spatiotemporal characteristics of neurophysiological changes in patients with four-repeat tauopathies.

Introduction: Progressive supranuclear palsy (PSP) and corticobasal degeneration (CBD), are the most common four-repeat tauopathies (4RT), and both frequently occur with varying degree of Alzheimer's disease (AD) copathology. Intriguingly, patients with 4RT and patients with AD are at opposite ends of the wakefulness spectrum-AD showing reduced wakefulness and excessive sleepiness whereas 4RT showing decreased homeostatic sleep. The neural mechanisms underlying these distinct phenotypes in the comorbid condition of 4RT and AD are unknown.

Confined Lewis Pairs: Investigation of the X →Si Interaction in Halogen-Encapsulating Silafulleranes.

A joint theoretical and experimental study on 32 endohedral silafullerane derivatives [X@Si Y ] (X=F-I; Y=F-I, H, Me, Et) and -[Cl@Si H Y ] (Y=F-I) is presented. First, we evaluated the structure-determining template effect of Cl in a systematic series of concave silapolyquinane model systems. Second, we investigated the X →Si interaction energy ( ) as a function of X and Y and found the largest values for electron-withdrawing exohedral substituents Y.

Accuracy in static guided implant surgery: Results from a multicenter retrospective clinical study on 21 patients treated in three private practices.

Purpose: To evaluate the accuracy of a static computer-assisted implant surgery (s-CAIS) system across different private practices.

Methods: This retrospective clinical study was based on data retrieved from 21 patients who received 61 implants between 2018 and 2020 in 3 private practices run by surgeons with extensive experience with s-CAIS. All patients were treated using the same s-CAIS system, planning software, template manufacturing process, and surgical guides.

Trueness, precision, time-efficiency and cost analysis of chairside additive and subtractive versus lab-based workflows for manufacturing single crowns: An in vitro study.

Purpose: To evaluate the trueness, precision, time efficiency, and cost of three different workflows for manufacturing single crowns (SCs).

Methods: A plaster model with a prepared tooth (#15) was scanned with an industrial scanner, and an SC was designed in computer-assisted-design (CAD) software. Ten SCs were printed with a hybrid composite (additive chairside) and a stereolithographic (SLA) printer (Dfab®), 10 SCs were milled in lithium disilicate (subtractive chairside) using a chairside milling unit (inLab MC XL®), and 10 SCs were milled in zirconia (lab-based) using a five-axis laboratory machine (DWX-52D®).

B,N-Doped Heptacenes: Ambipolar Charge-Transfer Compounds with Deep LUMO Levels.

The B,N-doped heptacene in which two ,'-dihydrophenazine units are linked by two BMes bridges (Mes = mesityl) was synthesized via fourfold Buchwald-Hartwig coupling between 2,3,6,7-tetrachloro-9,10-dimesityl-9,10-dihydro-9,10-diboraanthracene and -phenylenediamine (BuXPhos-Pd-G3, DBU/NaOTf, 2-MeTHF, 50 °C, 16 h). Upon exposure to ambient air, is oxidized to its ,'-dihydro form ; further oxidation with MnO furnishes the di(phenazine) derivative . Stirring under a blanket of H in the presence of Pd/C hydrogenates back to and ultimately .

Full-arch restoration with the NEXUS IOS® system: A retrospective clinical evaluation of 37 restorations after a one year of follow-up.

Objectives: Report the results with a novel workflow of digital restoration for completely edentulous patients with implant supported full arch fixed dental prostheses (ISFDP).

Methods: This multicenter retrospective clinical study was based on the evaluation from a cohort of 29 patients restored with 37 ISFDP designed and manufactured from the data captured by a direct intraoral scan, using a novel full digital system (NEXUS IOS®, Osteon Medical, a Keystone Dental Group company, Melbourne, Australia). Data was collected over a 3-year period, in six different dental centers.

Vicinal Vinylation of Boron-Doped Acenes via Heck Coupling.

Silylated and halogenated benzenes 1,2-(MeSi)-4,5-X-CH [X = Br (), I ()] are versatile synthetic building blocks. was prepared from known 1,2-(MeSi)-4,5-Cl-CH via C-Cl borylation/bromodeboronation; CuI-catalyzed Br/I exchange on affords . or and BBr yield 9,10-dibromo-9,10-dihydro-9,10-diboraanthracenes (DBAs) or .

Biodegradable Mineral Plastics.

Mineral plastics are a promising class of bio-inspired materials that offer exceptional properties, like self-heal ability, stretchability in the hydrogel state, and high hardness, toughness, transparency, and non-flammability in the dry state along with reversible transformation into the hydrogel by addition of water. This enables easy reshape-ability and recycling like the solubility in mild acids to subsequently form mineral plastics again by base addition. However, current mineral plastics rely on petrochemistry, are hardly biodegradable, and thus persistent in nature.

Brominated [20]silafulleranes: pushing the limits of steric loading.

Starting from the perhydrogenated silafullerane [BuN][Cl@Si(SiH)H], treatment with BBr leads to partially and exhaustively brominated clusters, [BuN][Cl@Si(SiBrH)Br] (120 eq. BBr, room temperature, 30 min) and [BuN][Cl@Si(SiBr)Br] (300 eq. BBr, 130 °C, 3 d).