Publications by authors named "Lerch D"

In recent years, the subject of deep reinforcement learning (DRL) has developed very rapidly, and is now applied in various fields, such as decision making and control tasks. However, artificial agents trained with RL algorithms require great amounts of training data, unlike humans that are able to learn new skills from very few examples. The concept of meta-reinforcement learning (meta-RL) has been recently proposed to enable agents to learn similar but new skills from a small amount of experience by leveraging a set of tasks with a shared structure.

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Background: In accordance with legal requirements, the Federal Joint Committee (German: Gemeinsamer Bundesausschuss, G‑BA) decides based on the best available evidence which new diagnostic and treatment methods are reimbursed by statutory health insurance. If the benefit is proven with sufficient certainty, statutory health insurance providers pay for the new method, otherwise a trial study must be conducted.

Objectives: To present the G‑BA's decision-making options even in the case of insufficient evidence in the field of urology.

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Massive declines in insect biodiversity and biomass are reported from many regions and habitats. In urban areas, creation of native wildflower meadows is one option to support insects and reduce maintenance costs of urban green spaces. However, benefits for insect conservation may depend on previous land use, and the size and location of new wildflower meadows.

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Purpose: To describe our technique of sub-Tenon's anesthesia and report adverse events and patient comfort.

Setting: Optical Express, United Kingdom.

Design: Retrospective case series.

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Background: Age, smoking, hypercholesterolemia, and hypertension are major risk factors for atherosclerotic cardiovascular disease.

Objective: We examined whether the effects of alirocumab on low-density lipoprotein cholesterol (LDL-C) differed according to age, hypertension, or smoking status.

Methods: Data were pooled from 10 Phase 3 ODYSSEY randomized trials (24-104 weeks' duration) in 4983 people with heterozygous familial hypercholesterolemia (FH) or non-familial hypercholesterolemia (3188 on alirocumab, 1795 on control [620 on ezetimibe and 1175 on placebo]).

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A CT system with a tablet as mobile user interface and a wireless remote control for positioning and radiation release has recently been presented. Our aim was to evaluate the effects of a mobile CT examination workflow on the radiographers' performance compared to conventional examinations. A prototype of a radiation protection cabin was installed besides the gantry of a CT system.

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The stability of various point defects in NiAl(100) has been investigated by first-principles calculations. For Al-rich surfaces, Ni vacancies within the first Al layer are energetically most favourable. For Ni-rich surfaces, so-called double defects, consisting of both Ni-antisite atom in the first Al layer and a Ni vacancy within the second Ni layer, form the configuration of lowest energy, superior to singular Ni antisites.

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