Publications by authors named "Leqiang Du"
Article Synopsis
- High-temperature stress significantly harms aquatic organisms like tsinling lenok trout (Brachymystax lenok tsinlingensis), prompting a study on microRNAs (miRNAs) and their role in liver inflammation under such conditions.
- The study exposed trout to high temperatures (24 °C) for 8 hours, identifying miRNAs that were differentially expressed compared to a control group (16 °C), with two notable miRNAs, novel-m0105-5p and miR-8159-x, linked to inflammatory response pathways.
- The researchers confirmed that these miRNAs enhance liver inflammation by promoting the expression of target genes NFKB1 and MAP3K5, highlighting the importance of understanding these mechanisms for improving fish
Tsinling lenok trout (Brachymystax lenok tsinlingensis) is a typical cold water fish. High temperature has been shown to damage the liver of fish. However, few studies have investigated the liver apoptosis induced by high temperature stress in fish from the perspective of gene expression and metabolic function.
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