Publications by authors named "Leopold Oliver"
Background: In native mitral valve infective endocarditis (NMIE), the respective values of mitral valve repair (MVRep) and replacement (MVR) are still debated.
Aim: To compare MVRep and MVR in a large prospective matched cohort.
Methods: Between 2010 and 2017, all consecutive patients operated on for NMIE in our centre were included prospectively.
Article Synopsis
- F-FDG PET/CT is now included in the ESC 2015 guidelines for diagnosing infective endocarditis, but its effectiveness in native valve endocarditis (NVE) is not fully understood.
- A study involving 75 patients identified that while F-FDG PET/CT had low sensitivity (17.5%) for diagnosing NVE, it maintained high specificity (100%) and was effective for detecting embolic events.
- The research also revealed a new diagnostic feature of diffuse splenic uptake seen in over half of the patients with NVE, suggesting its potential utility in clinical practice.
Article Synopsis
- Multimodality imaging, particularly transesophageal echocardiography (TEE) and cardiac computed tomography (CT), is crucial for diagnosing infective endocarditis (IE) in patients prior to surgery.
- A study of 68 patients with left-side IE found TEE was more effective than CT in identifying valvular lesions and had similar performance for paravalvular lesions.
- TEE showed significantly better detection of vegetations compared to CT, while CT had higher sensitivity for pseudoaneurysms; however, both methods had comparable overall diagnostic accuracy for paravalvular lesions.
Article Synopsis
- The study aimed to evaluate the effectiveness of F-FDG-PET/CT as part of the ESC criteria for diagnosing prosthetic valve infective endocarditis (PVE), while also comparing it to traditional echocardiography.
- Researchers analyzed data from 175 patients suspected of having PVE, ultimately focusing on 115 patients whose F-FDG-PET/CT results were interpretable.
- Results showed that while F-FDG-PET/CT increased the sensitivity of the ESC criteria compared to the Duke criteria, it also decreased specificity, and the presence of diffuse splenic uptake was notable in a significant portion of patients with definitive PVE.
Aims: The EURO-ENDO registry aimed to study the management and outcomes of patients with infective endocarditis (IE).
Methods And Results: Prospective cohort of 3116 adult patients (2470 from Europe, 646 from non-ESC countries), admitted to 156 hospitals in 40 countries between January 2016 and March 2018 with a diagnosis of IE based on ESC 2015 diagnostic criteria. Clinical, biological, microbiological, and imaging [echocardiography, computed tomography (CT) scan, 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT)] data were collected.
Background: F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) is commonly used for the diagnosis of infective endocarditis (IE), but its prognostic value remains unknown.
Objectives: This study sought to assess the prognostic value of F-FDG PET/CT in prosthetic valve endocarditis (PVE) and native valve endocarditis (NVE).
Methods: This study prospectively included 173 consecutive patients (109 PVE and 64 NVE) with definite left-sided IE who had an F-FDG PET/CT and were followed-up for 1 year.
Background: Bacterial infective endocarditis (IE) is rarely suspected in patients with a low C-reactive protein (CRP) concentration.
Aims: To address the incidence, characteristics and outcome of left-sided valvular IE with low CRP concentration.
Methods: This was a retrospective analysis of cases of IE discharged from our institution between January 2009 and May 2017.
Article Synopsis
- The study aimed to assess the effectiveness and safety of a new treatment regimen combining intravenous trimethoprim-sulfamethoxazole and clindamycin (T&C) for Staphylococcus aureus endocarditis compared to traditional treatments.
- It involved 341 patients, with 170 receiving standard treatment before 2012 and 171 receiving the T&C protocol after implementation in 2012.
- Results showed that the T&C group had lower global, in-hospital, and 30-day mortality rates and a significantly shorter average hospital stay compared to the control group.
Background: The inferior vena cava (IVC) has a complex three-dimensional (3D) shape, but measurements used to estimate central venous pressure (CVP) remain based on two-dimensional (2D) echocardiographic imaging. The aim of this study was to investigate the accuracy of IVC size and collapsibility index obtained by 3D echocardiography for assessing CVP in patients with cardiogenic shock.
Methods: Eighty consecutive echocardiographic examinations performed in 33 patients (mean age, 72 ± 15 years; mean left ventricular ejection fraction, 19 ± 10%) admitted for cardiogenic shock were prospectively included.
Background: The outcome of cardiac amyloidosis (CA) has been reported mainly in stable populations; limited data are available in patients referred for acute heart failure (AHF) to an intensive cardiac care unit (ICCU).
Aims: To address the characteristics and outcomes of patients with confirmed CA admitted to an ICCU for AHF and then to identify the predictors of evolution to cardiogenic shock.
Methods: All patients with CA referred to an ICCU for AHF between 2009 and 2015 were included.
Objective: To describe the characteristics of infective endocarditis (IE) in octogenarians and assess their prognosis.
Methods: Patients with definite IE hospitalised at a referral centre between July 2008 and July 2013 were prospectively included. A total of 454 patients were divided into three groups: 230 patients under 65 years old, 173 patients between 65 and 80 years old, and 51 patients over 80 years old.
Background: Diagnosis of hypertrophic cardiomyopathy (HCM) in athletes can be challenging.
Aims: To ascertain parameters that differentiate patients with HCM from athletes with moderate left ventricular (LV) hypertrophy (LVH 13-15mm).
Methods: We retrospectively included 100 men: 50 elite rugby players (25 with moderate LVH and 25 with no LVH), 25 patients with HCM and moderate LVH and 25 controls.