Publications by authors named "Leopold C Barthel"
Article Synopsis
- Antimicrobial peptides (AMP) are crucial for protecting epithelial surfaces from harmful microorganisms, with significant differences noted in their expression between oral and extraoral tissues.
- Research utilizing real-time PCR, immunohistochemistry, and western blot techniques demonstrated that hBD-1, hBD-2, hBD-3, and psoriasin are expressed more in the oral mucosa than in skin, suggesting a stronger protective role in the mouth.
- Findings indicate potential for developing new treatments based on AMP derivatives, particularly targeting the variances in their expression levels between these two types of epithelium.