Publications by authors named "Leonora De Zorzi Piccoli"
We aimed to report the experience in managing action research on hepatitis C investigation in the prison community in the Triângulo Mineiro region, Minas Gerais, Brazil. The proposal was developed from March 2019 to March 2020, reaching 240 people to contain the spread of the disease through a survey, testing, and monitoring of positive cases. We adopted intersectoral action with articulation between Universities, Medical Society, Teaching Hospital, and State Secretariat for Justice and Public Security.
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- The study assessed the effectiveness of retreatment for hepatitis C in patients who did not respond to previous direct antiviral agents (DAA), highlighting Brazil's adherence to updated health guidelines.
- The survey gathered clinical and epidemiological data from institutions nationwide, focusing on those previously treated with interferon-free regimens.
- Results showed a 94.6% sustained virological response rate in patients retreated, indicating that the available retreatment options in Brazil are both effective and safe, supporting efforts to eliminate hepatitis C.
Context: Chronic hepatitis C as well as non-alcoholic fatty liver disease are recognized as the main cause of liver disease in Western countries. It is common to see the concomitance of the diseases and the influence of steatosis in the sustained virological response of patients with hepatitis C virus.
Objective: Assess the sustained virological response in chronic hepatitis C patients according to the presence of liver steatosis.