Publications by authors named "Leonor Moreno-Nunez"
Objective: To evaluate the adequacy of empirical antibiotic prescription and the duration of antibiotic therapy for infected patients admitted for conventional hospitalization (CH) and Hospitalization at Home (HaH) after implementation of an antibiotic stewardship programs (ASP) in HaH.
Design: Retrospective cohort study.
Patients: Patients admitted for infection to Emergency Department between October and December 2023.
Article Synopsis
- The study aimed to analyze how dalbavancin was used to treat infections in diabetic patients across Italian and Spanish clinics.
- The research involved 97 adults with diabetes and highlighted that most treatments were for Gram-positive infections, primarily cellulitis and Staphylococcus aureus.
- The findings suggest dalbavancin was recommended for its simplicity in antibiotic regimens and resulted in a high rate of clinical improvements for patients.
Objective: Corynebacterium striatum (CS) is an emerging micro-organism in diabetic foot infection for which there are currently few studies. The objective was to analyze the risk factors (RF) related to CS osteomyelitis in patients with diabetic foot.
Methods: A case-control study was conducted in the Diabetic Foot Unit between 2015 and 2021.
Article Synopsis
- Ceftobiprole medocaril (Cefto-M) is a fifth-generation antibiotic approved in Europe for pneumonia treatment, and a study was conducted in Spain to evaluate its use in clinical practice from September 2021 to December 2022.
- The study included 249 patients, mostly older adults with various infections, with respiratory infections being the most common; 67.9% received Cefto-M as empirical treatment, typically as monotherapy for about one week.
- The results showed an 11.2% infection-related mortality, with higher rates in patients with severe conditions like ventilator-associated pneumonia and sepsis, indicating that Cefto-M is generally safe and often used as a last-resort option
Respiratory syncytial virus infection in adults: Differences with influenza.
Enferm Infecc Microbiol Clin (Engl Ed)
February 2024
Introduction: Respiratory syncytial virus (RSV) causes an acute respiratory illness similar to influenza, although there are few data comparing both of them in adults. The existence of clinical differences between these two infections could have implications for their management.
Materials And Methods: Retrospective observational cohort study including 63 adults with positive PCR for RSV and 221 for influenza during winter 2018-2019.
Antibiotic discontinuation through an antibiotic treatment optimization program in emergency department patients with low suspicion of infection.
Enferm Infecc Microbiol Clin (Engl Ed)
November 2022
Introduction: One of the most important strategies of PROA in the Emergency Department (ED) is the accurate diagnosis of infection to avoid inappropriate prescription. Our objective is to evaluate patients who receive antibiotics despite not having objective data of infection.
Methods: We carried out a cross-sectional study of patients admitted to the ED of the Hospital Universitario Fundación Alcorcón in which it was recommended to suspend the antibiotic through the PROA.
Experience in the use of dalbavancin in diabetic foot infection.
Enferm Infecc Microbiol Clin (Engl Ed)
June 2022
Objective: To describe the clinical experience with dalbavancin in the treatment of diabetic foot infection in a multidisciplinary unit of a second level hospital.
Methods: A retrospective, descriptive study was made with all patients with diabetic foot infection treated with dalbavancin in the Diabetic Foot Unit of Hospital Universitario Fundación Alcorcón, covering the period from September 2016 to December 2019. Demographic parameters and comorbidities, characteristics of the infection and treatment with dalbavancin were recorded.
Experience in the use of dalbavancin in diabetic foot infection.
Enferm Infecc Microbiol Clin (Engl Ed)
January 2021
Objective: To describe the clinical experience with dalbavancin in the treatment of diabetic foot infection in a multidisciplinary unit of a second level hospital.
Methods: A retrospective, descriptive study was made with all patients with diabetic foot infection treated with dalbavancin in the Diabetic Foot Unit of Hospital Universitario Fundación Alcorcón, covering the period from September 2016 to December 2019. Demographic parameters and comorbidities, characteristics of the infection and treatment with dalbavancin were recorded.
Safety and Tolerability of More than Six Days of Tedizolid Treatment.
Antimicrob Agents Chemother
June 2020
Tedizolid has demonstrated its efficacy and safety in clinical trials; however, data concerning its tolerability in long-term treatments are scarce. The aim of the study was to assess the indications and to describe the long-term safety profile of tedizolid. A multicentric retrospective study of patients who received tedizolid for more than 6 days was conducted.
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