Single-channel response of hamster oocytes to fertilization with homologous spermatozoa.

Electrophysiological events occur early after fertilization, along with changes in intracellular Ca2+ concentration. Passive electrical parameters were determined in golden hamster oocytes by whole cell patch-clamp method. In separate experiments the effect of 4-aminopyridine on resting oocytes was tested.

Chronic hypobaric hypoxia effects on rat colon in vitro sensitivity to acute hypoxia and amiloride.

Chronic hypoxia induces many physiological changes, but little is known about its effects on colonic epithelial function. Isolated distal colon mucosa from rats under normobaric conditions and rats submitted to hypobaric hypoxia for either 4 or 10 days was studied in an Ussing chamber. After 4 days of hypoxia, there was only a 15% increase in transepithelial resistivity.