Contribution of a natural polymorphism in protein kinase G modulates electroconvulsive seizure recovery in .

is a well-characterized model for neurological disorders and is widely used for investigating causes of altered neuronal excitability leading to seizure-like behavior. One method used to analyze behavioral output of neuronal perturbance is recording the time to locomotor recovery from an electroconvulsive shock. Based on this behavior, we sought to quantify seizure susceptibility in larval with differences in the enzymatic activity levels of a major protein, cGMP-dependent protein kinase (PKG).