Long Noncoding RNA UCA1 Correlates With Electropathology in Patients With Atrial Fibrillation.

Background: Perpetuation of atrial fibrillation (AF) is rooted in derailment of molecular proteostasis pathways that cause electrical conduction disorders that drive AF. Emerging evidence indicates a role for long noncoding RNAs (lncRNAs) in the pathophysiology of cardiac diseases, including AF.

Objectives: In the present study, the authors explored the association between 3 cardiac lncRNAs and the degree of electropathology.