Publications by authors named "Leonie van Rheenen-Flach"

Background: With the global increase of cesarean deliveries, breech presentation is the third indication for elective cesarean delivery. Implementation of external cephalic version (ECV), in which the position of the baby is manipulated externally to prevent breech presentation at term, remains suboptimal. Increasing knowledge for caretakers and patients is beneficial in the uptake of ECV implementation.

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Objective: Assess the outcome of induction of labour (IOL) with a Foley catheter in pregnancies at 41 weeks in midwifery-led care setting compared to consultant-led care setting.

Design: Mixed-methods cohort study at a midwifery - hospital partnership in Amsterdam, the Netherlands.

Setting And Participants: Prospectively, women undergoing IOL in midwifery-led care were recruited at a secondary hospital.

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Article Synopsis
  • The study aimed to assess the rates of depression, anxiety, and PTSD among women years after experiencing hyperemesis gravidarum (HG) and how these mental health issues relate to the severity of HG symptoms.
  • A cohort of 215 women who had been hospitalized for HG provided data through questionnaires measuring anxiety, depression, and PTSD both six weeks and approximately 4.5 years postpartum.
  • Results indicated that a significant number of participants experienced elevated levels of anxiety (39.7%) and depression (27.4%) during follow-up, alongside a notable prevalence of PTSD (21.9%), with increased HG severity linked to higher mental health risk scores.
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Article Synopsis
  • The study explored how the severity of hyperemesis gravidarum (HG) in pregnant women affected cardiometabolic markers in their babies' cord blood.
  • It found that lower maternal weight gain was linked to higher levels of glucose and Apo-B in the cord blood, but other measures of HG severity and the use of enteral tube feeding did not show significant associations.
  • Overall, while lower weight gain was a notable factor, the study concluded that other HG severity factors and enteral tube feeding did not impact the cardiometabolic markers in the offspring.
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Article Synopsis
  • Hyperemesis gravidarum (HG) affects 1% of pregnancies and significantly impacts women's quality of life, raising concerns about its long-term effects and recurrence in future pregnancies.
  • The study followed 73 women previously hospitalized for HG to measure recurrence rates, instances of postponed or terminated pregnancies due to HG, and identify predictive factors for recurrence.
  • Results showed that 89% of subsequent pregnancies experienced HG recurrence, with 40% of women postponing pregnancy plans, and some considering termination due to HG symptoms.
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Introduction: Little is known about the pathophysiology of hyperemesis gravidarum (HG). Proposed underlying causes are multifactorial and thyroid function is hypothesized to be causally involved. In this study, we aimed to assess the utility of thyroid-stimulating hormone (TSH) and free thyroxine (FT4) as a marker and predictor for the severity and clinical course of HG.

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Background: The clinical dilemma on the preferred mode of delivery for breech position still exists. Elective caesarean delivery (CD) could be safer for neonates, whereas vaginal breech delivery (VBD) remains a safe option when conducted by an experienced person. Besides successful VBD is beneficial for mothers and subsequent pregnancies.

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Objective: We aimed to identify determinants that predict hyperemesis gravidarum (HG) disease course and severity.

Study Design: For this study, we combined data of the Maternal and Offspring outcomes after Treatment of HyperEmesis by Refeeding (MOTHER) randomized controlled trial (RCT) and its associated observational cohort with non-randomised patients. Between October 2013 and March 2016, in 19 hospitals in the Netherlands, women hospitalised for HG were approached for study participation.

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Objective: To assess adherence to the national postpartum hemorrhage guideline and Managing Obstetric Emergencies and Trauma course instructions and its determinants in the Netherlands.

Methods: A prospective observational multicenter study in 16 Dutch hospitals analyzing data from medical records of 398 women at high risk for postpartum hemorrhage, of which 293 were supplemented with data from prospective video recordings. Adherence to guideline-based quality indicators for prevention, management, and organization of postpartum hemorrhage care was measured.

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In this article, we discuss possible explanations for the discrepancy in results between urine and blood pregnancy tests. The first patient, a 26-year-old woman, had breast tenderness, was tired and suffered from abdominal pain. A urine pregnancy test was negative, but blood human chorion gonadotropin (hCG) concentration was 455 U/l (reference value < 6 U/l).

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Background: Rotation thromboelastometry (ROTEM) is an easy, fast and complete method of measuring coagulation.

Aims: Our goal was to obtain longitudinal values on ROTEM in uncomplicated pregnancies and in the puerperium.

Materials And Methods: Healthy women, who visited our outpatient clinic for antenatal checks and who accomplished an uncomplicated pregnancy were tested three times during pregnancy and one time postpartum.

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