Diagnostic precision of fecal calprotectin for inflammatory bowel disease and colorectal malignancy.

Objectives: Fecal calprotectin (FC) is a relatively new marker of intraluminal intestinal inflammation. Using meta-analytical techniques, the study aimed to evaluate the diagnostic precision of FC for inflammatory bowel disease (IBD) and colorectal cancer (CRC) in adults and children.

Methods: Quantitative meta-analysis was performed on prospective studies, comparing FC levels against the histological diagnosis.