Publications by authors named "Leonel Stein"
Objective: To compare the effectiveness of the awake-prone position on relevant clinical outcomes in patients with COVID-19-related acute respiratory failure requiring high-flow nasal oxygen between different waves in Argentina.
Methods: This multicenter, prospective cohort study included adult patients with COVID-19-related acute respiratory failure requiring high-flow nasal oxygen. The main exposure position was the awake-prone position (≥ 6 hours/day) compared to the non-prone position.
Article Synopsis
- A study was conducted to evaluate the effectiveness of the awake-prone position for patients with COVID-19-related acute respiratory failure requiring high-flow nasal oxygen in Argentina.
- The study included 728 patients across two waves of the pandemic, comparing outcomes like endotracheal intubation and in-hospital mortality between those in the awake-prone position and those in a non-prone position.
- Results showed that the awake-prone position significantly reduced the risk of both endotracheal intubation and in-hospital mortality, with consistent benefits observed across different waves of the pandemic.