CYP2D6 isoenzyme and ABCB1 gene polymorphisms associated with postoperative nausea and vomiting in women undergoing laparoscopic cholecystectomy: a randomized trial.

Introduction: Postoperative nausea and vomiting is still a common complication. Serotonin receptor antagonists are commonly used in clinical practice for antiemetic prophylaxis. Interindividual variations in drug response, including single nucleotide polymorphisms, are related to pharmacokinetic and pharmacodynamic changes in these drugs and may lead to a poor therapeutic response.

Genetic polymorphism in the tumour necrosis factor alpha gene (G-308A) is associated with persistent apical periodontitis in Brazilians.

Aim: To investigate if there was an association between genetic polymorphisms in tumour necrosis factor (TNF)-⍺ and its receptors TNFRSF1A and TNFRSF1B with persistent apical periodontitis (PAP) in Brazilian subjects.

Methodology: Patients who had pulpal necrosis and apical periodontitis at the time of treatment, with at least 1-year of follow-up after non-surgical root canal treatment were recalled. Three hundred and seventy eight subjects were included, 150 subjects with signs/symptoms of PAP and 228 subjects with root canal-treated teeth exhibiting healthy perirradicular tissues (healed).

Assessment of oral health-related quality of life in adolescents, young adults, and adults with dental agenesis: A comparative study.

Aim: To detect the impact on oral health-related quality of life (OHRQoL) in adolescents, young adults, and adults with dental agenesis (DA).

Methods: A comparative study (1:2) matched for age and sex was designed. Data of participants, aged 14-55 years (group with DA: G1; group without DA: G2), and who answered the Brazilian version of the Oral Health Impact Profile-14 questionnaire, were collected.

Effect of the antimicrobial photodynamic therapy on microorganism reduction in deep caries lesions: a systematic review and meta-analysis.

This study aimed to perform a systematic review to assess the effectiveness of antimicrobial photodynamic therapy (aPDT) in the reduction of microorganisms in deep carious lesions. An electronic search was conducted in Pubmed, Web of Science, Scopus, Lilacs, and Cochrane Library, followed by a manual search. The MeSH terms, MeSH synonyms, related terms, and free terms were used in the search.

TGFB3 and BMP4 polymorphism are associated with isolated tooth agenesis.

Objective: To evaluate the association of the polymorphisms in the TGFB3 gene (rs2268626) and the BMP4 gene (rs17563) with isolated human tooth agenesis.

Materials And Methods: One hundred and seventy-five unrelated individuals (125 control individuals without tooth agenesis and 50 cases with tooth agenesis) were evaluated using a case-control design. The participants of the study were recruited through the Dental School of the Federal University of Rio de Janeiro, Brazil.

Topography and presence of a smear layer in deciduous molars prepared with high-speed cutting and ultrasonic abrasion: an in-vitro study.

Objective: The aim of this in-vitro study was to compare the effect of high-speed cutting (HS) with ultrasonic abrasion (US) concerning the internal topography and the presence of a smear layer in a cavity preparation performed in healthy deciduous molars.

Material And Methods: Seven first deciduous molars were used. Two occlusal cavity preparation were done, one in the medial fossula and another in the distal fossula, which were chosen randomly.

Educative practices and attitudes within the pre-school environment: evaluating the education professionals.

School and family together play an important role in the individual development of children. Therefore, this study aimed at evaluating the practices and attitudes towards oral health care of 245 education professionals working in 24 public municipal pre-schools in Niterói, State of Rio de Janeiro, Brazil. The data were obtained from self-questionnaires consisting of both open and closed questions.

[Breast-feeding as a source of prevention in healthcare].

The importance of breast-feeding has been addressed through multi-professional approaches. As healthcare practitioners, dentists are included in this context and - due to the close links between breast-feeding and the development of the stomatognathic system - should be able to advise pregnant women and new mothers on this practice, with countless benefits for mothers and their babies. This paper thus presents up-to-date and enlightened information through a review of the literature that supports the benefits of breast-feeding, urging heightened awareness of its importance and the preparation of policies and actions implemented through Brazil's National Health System (SUS) that rank breast-feeding as a high-priority goal.