Publications by authors named "Leonardo Szalo Amendola"
The Prolonged Activation of the p65 Subunit of the NF-Kappa-B Nuclear Factor Sustains the Persistent Effect of Advanced Glycation End Products on Inflammatory Sensitization in Macrophages.
Sayonara Ivana Santos de Assis Leonardo Szalo Amendola Maristela Mitiko Okamoto Guilherme da Silva Ferreira Rodrigo Tallada Iborra
Int J Mol Sci
February 2024
Article Synopsis
- * Macrophages pre-treated with AGE-albumin released higher levels of inflammatory cytokines (TNF, IL-6, IL-1beta) compared to those treated with control albumin, with notable increases persisting for up to 24 hours.
- * The p65 subunit of nuclear factor kappa B (NFKB) shows prolonged activation in AGE-treated macrophages, suggesting that targeting this pathway could help manage inflammation-related complications.