Virologic Failure, Clinical Characteristics, and Common Viral Mutations in HIV Patients From Southwestern Colombia: A Nested Case-Control Study.

Introduction Virologic failure due to antiretroviral drug resistance is a threat to efforts to control the human immunodeficiency virus (HIV) epidemic. Understanding the factors that influence the genetic and clinical expression of drug resistance is fundamental for infection control. Methods A nested case-control study was conducted on a cohort of adult HIV patients between 2016 and 2022.

An investigation of the parameter space for a family of dissipative mappings.

The parameter plane investigation for a family of two-dimensional, nonlinear, and area contracting map is made. Several dynamical features in the system such as tangent, period-doubling, pitchfork, and cusp bifurcations were found and discussed together with cascades of period-adding, period-doubling, and the Feigeinbaum scenario. The presence of spring and saddle-area structures allow us to conclude that cubic homoclinic tangencies are present in the system.