[Primary amenorrhea and XY karyotype: identifying patients in risk].

Purpose: to verify the prevalence and clinical characteristics of patients with primary amenorrhea and XY karyotype, evaluated in our Service, aiming at identifying findings which could help their recognition.

Methods: from January 1975 to November 2007, 104 patients with amenorrhea were evaluated. All the cases were analyzed by the karyotype by GTG bands.

MnSOD gene polymorphism association with steroid-dependent cancer.

Oxidative stress enhances carcinogenesis due to DNA damage. Manganese superoxide dismutase (MnSOD) Val16Ala polymorphism has been recently associated with breast and prostate cancer. The role of oxidative stress in male breast cancer is poorly investigated due to the low prevalence of this neoplasia.