Publications by authors named "Leonardo Hermes Dutra"
Article Synopsis
- - Rotavirus A (RVA), a key cause of gastroenteritis worldwide, has seen the rise of a specific strain, G3P[8], in Brazil since 2015, which was extensively studied through stool samples and genetic analysis across multiple states.
- - Phylogenetic analysis revealed that this G3P[8] strain became dominant in Brazil by 2020, with a significant presence of equine-like variants, suggesting it originated in Asia and spread globally through various introductions between 2014 and 2017.
- - The study highlights that while most genetic changes in the G3P[8] strain were not adaptive, ongoing genomic surveillance is crucial for tracking its evolution and informing public health strategies
The Spike protein's structure of the SARS-CoV-2 provides a unique opportunity to consider perturbations at the atomic level. We used the cryo-electron microscopy structure of the open conformation of the Spike protein to assess the impact of the mutations observed in the variants of concern at the molecular level. Molecular dynamics were subsequently performed with both the wt and the mutated forms to compare the flexibility and variation data for each residue of the three-dimensional fluctuations in the region associated with each alpha carbon.
View Article and Find Full Text PDFBackground: Chikungunya virus (CHIKV) emerged in the Americas in 2013 and has caused approximately 2.1 million cases and >600 deaths. A retrospective investigation was undertaken to describe clinical, epidemiological, and viral genomic features associated with deaths caused by CHIKV in Ceará state, northeast Brazil.
View Article and Find Full Text PDFEhrlichiosis is a disease caused by rickettsial organisms belonging to the genus Ehrlichia. In Brazil, molecular and serological studies have evaluated the occurrence of Ehrlichia species in dogs, cats, wild animals and humans. Ehrlichia canis is the main species found in dogs in Brazil, although E.
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