Publications by authors named "Leonardo Dozza de Sousa"
Placebo-controlled efficacy of 5-HT3 antagonists for postoperative nausea and vomiting prophylaxis in supratentorial craniotomies: A systematic review and comparative meta-analysis of randomized clinical trials.
Marcio Yuri Ferreira Gabriel Scarpioni Barbosa João Damásio da Costa Neto Gustavo de Oliveira Almeida Silvio Porto Junior Leonardo Dozza de Sousa Marcelo Porto Sousa
Clin Neurol Neurosurg
November 2024
Article Synopsis
- * A total of five randomized controlled trials involving 347 patients were analyzed, showing that those receiving 5-HT3 antagonists had significantly lower rates of vomiting and nausea compared to the placebo group within the first 24 hours post-surgery.
- * The results support the use of 5-HT3 antagonists in clinical settings to reduce PONV after neurosurgery, with evidence indicating better outcomes compared to placebo treatments.