Publications by authors named "Leonardo Cruz-Reynoso"

Background Adequate nutritional support is crucial for achieving optimal growth and development in very-low-birth-weight (VLBW) preterm infants. This study evaluated the efficacy of combined nutrition (CN) (parenteral plus enteral nutrition (EN)) as an alternative nutrition protocol for VLBW infants in the neonatal intensive care unit (NICU). Methods This retrospective cohort study collected clinical and growth data from the medical records of VLBW infants weighing between 1,000 and 1,500 grams in the NICU of the Hospital of Obstetrics and Gynecology "Dr.

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Article Synopsis
  • Early onset neonatal sepsis (EOS) is a significant public health issue, and unnecessary antibiotic treatment can worsen health outcomes; using an EOS risk calculator can help reduce this problem.
  • A study compared antibiotic use and hospital stay durations in newborns before and after implementing the EOS risk calculator, finding that no significant difference in EOS diagnoses occurred between the two groups.
  • Results showed that after using the EOS risk calculator, 46.7% of infants received antibiotics compared to 100% before its implementation, indicating the calculator's effectiveness in minimizing unnecessary antibiotic use.
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Necrotizing enterocolitis (NEC) is an inflammatory bowel disease and a leading cause of morbidity and mortality in preterm infants. In this study, a randomized double-blind parallel-group (1:1) trial was carried out in two neonatal intensive care units of two tertiary hospitals. Two hundred and twenty-five preterm newborns with an expected functional gastrointestinal tract were recruited and received an enteral dose of 75 mg of docosahexaenoic acid (DHA)/kg body weight or high-oleic sunflower oil daily for 14 days from the first enteral feed after birth.

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Background: Pregnancy in patients with systemic lupus erythematosus is considered a high risk one since it is associated with a higher rate of maternal-fetal complications compared with the pregnancies in healthy women.

Objectives: The aim of this study was to describe the maternal-fetal outcomes in a cohort of Mexican patients with systemic lupus erythematosus and to identify risk factors associated with adverse maternal and fetal outcomes.

Patients And Methods: A cohort of pregnant lupus patients was analyzed.

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Article Synopsis
  • SARS-CoV-2 infection poses high risks to pregnant women and their newborns, with a case report from a hospital in Mexico detailing a neonate born to a COVID-19 positive mother.
  • The male newborn, delivered at 34 weeks, needed respiratory support due to the effects of sedative medications the mother had received during delivery, but showed improvement during his hospital stay.
  • Testing for SARS-CoV-2 in the newborn returned negative, raising questions about the possibility of vertical transmission of the virus from mother to child.
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Background: Retinopathy of prematurity (ROP) is a disorder of the retina of low-birth-weight preterm infants that potentially leads to blindness. Docosahexaenoic acid (DHA), is protective in experimental models, but its administration as part of parenteral nutrition has shown inconsistent results. We test the effect of enteral DHA to prevent ROP and/or severity and to reduce hospital stay.

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Objectives: To develop quality of care (QoC) indicators, evaluate the quality of the processes of care (QPC) and clinical outcomes, and analyze the association between the QPC and severe clinical outcomes of preterm newborns admitted to neonatal intensive care units (NICUs).

Design: Mixed methods approach: (1) development of QoC indicators via modified RAND/UCLA method; (2) cross-sectional study of QoC evaluation and (3) multiple logistic regression analysis to ascertain the association between the QPC and severe clinical outcomes.

Setting: Two NICUs belonged to the Mexican Institute of Social Security in Mexico City.

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