Assessing muscle function and oxidative profile in criollo horses participating in long loop rodeo before and after exercise.

Criollo breed is quite popular in Brazil, mainly in the Southern Region, and the long loop rodeo is one of the main sports modality adapted to this breed. The purpose of this study was to assess changes in the muscle and oxidative functions caused by exercises practiced in this sports modality. Data such as exercising frequency, covered distance, mean duration time and number of runs, and blood samples at the following times: before the tournament, on the final day of the event, and 18-24 h after the end of the tournament were collected.

Forest cover percentage drives the peak biting time of Nyssorhynchus darlingi (Diptera: Culicidae) in the Brazilian Amazon.

Background: Deforestation is an important driver of malaria dynamics, with a relevant impact on mosquito ecology, including larval habitat availability, blood-feeding behaviour, and peak biting time. The latter is one of several entomological metrics to evaluate vectorial capacity and effectiveness of disease control. This study aimed to test the effect of forest cover percentage on the peak biting time of Plasmodium-uninfected and infected Nyssorhynchus darlingi females.

ZooTraits: An R shiny app for exploring animal trait data for ecological and evolutionary research.

Animal trait data are scattered across several datasets, making it challenging to compile and compare trait information across different groups. For plants, the TRY database has been an unwavering success for those ecologists interested in addressing how plant traits influence a wide variety of processes and patterns, but the same is not true for most animal taxonomic groups. Here, we introduce ZooTraits, a Shiny app designed to help users explore and obtain animal trait data for research in ecology and evolution.

Mutations Linked to Insecticide Resistance Not Detected in the or Genes in from Multiple Localities in Amazonian Brazil and Peru.

Indoor residual spray (IRS), mainly employing pyrethroid insecticides, is the most common intervention for preventing malaria transmission in many regions of Latin America; the use of long-lasting insecticidal nets (LLINs) has been more limited. Knockdown resistance () is a well-characterized target-site resistance mechanism associated with pyrethroid and DDT resistance. Most mutations detected in acetylcholinesterase-1 () and voltage-gated sodium channel () genes are non-synonymous, resulting in a change in amino acid, leading to the non-binding of the insecticide.

Bringing light onto the Raunkiæran shortfall: A comprehensive review of traits used in functional animal ecology.

Trait-based approaches elucidate the mechanisms underlying biodiversity response to, or effects on, the environment. Nevertheless, the Raunkiæran shortfall-the dearth of knowledge on species traits and their functionality-presents a challenge in the application of these approaches. We conducted a systematic review to investigate the trends and gaps in trait-based animal ecology in terms of taxonomic resolution, trait selection, ecosystem type, and geographical region.

Treatment patterns, healthcare resource utilization and costs of HER2-negative gastric/gastroesophageal junction cancer.

To describe treatment patterns, healthcare resource utilization and costs in HER2-negative gastric/gastroesophageal (G/GEJ) cancer in the USA. Retrospective IQVIA Adjudicated Closed Claims database analysis; patients with HER2-negative G/GEJ cancer initiating systemic therapy between October 2016 and December 2019 were identified. Among 1317 patients, platinum plus taxane regimens (54%) were common in neoadjuvant/adjuvant settings.

The cost impact of disease progression to metastatic castration-sensitive prostate cancer.

Metastatic prostate cancer (PC) is associated with declining survival rates and increased health care expenditure. However, there are few studies quantifying these increased costs. To estimate overall health care resource utilization and costs associated with progression to metastatic disease in Medicare or commercially insured patients with nonmetastatic castration-sensitive PC (nmCSPC) or previously undiagnosed PC.

Anthropogenic landscape decreases mosquito biodiversity and drives malaria vector proliferation in the Amazon rainforest.

Inter-relationships among mosquito vectors, Plasmodium parasites, human ecology, and biotic and abiotic factors, drive malaria risk. Specifically, rural landscapes shaped by human activities have a great potential to increase the abundance of malaria vectors, putting many vulnerable people at risk. Understanding at which point the abundance of vectors increases in the landscape can help to design policies and interventions for effective and sustainable control.

The risk of malaria infection for travelers visiting the Brazilian Amazonian region: A mathematical modeling approach.

Background: Human mobility between malaria endemic and malaria-free areas can hinder control and elimination efforts in the Amazon basin, maintaining Plasmodium circulation and introduction to new areas.

Methods: The analysis begins by estimating the incidence of malaria in areas of interest. Then, the risk of infection as a function of the duration of stay after t was calculated as the number of infected travelers over the number of arrived travelers.

The environmental footprint of health care: a global assessment.

Background: Health-care services are necessary for sustaining and improving human wellbeing, yet they have an environmental footprint that contributes to environment-related threats to human health. Previous studies have quantified the carbon emissions resulting from health care at a global level. We aimed to provide a global assessment of the wide-ranging environmental impacts of this sector.

Evolutionary aspects that guide the cultural transmission pathways in a local medical system in Northeast Brazil.

Most of the studies with a focus on pathways and biases of cultural transmission in different domains show that vertical transmission predominates over horizontal and oblique transmission, especially in traits linked to traditions and survival skills, such as local medicine. However, overestimation of the importance of vertical transmission has been an object of methodological criticism. Therefore, a statistical analysis with diachronic perspective may obtain more accurate results.

Hunters' preferences and perceptions as hunting predictors in a semiarid ecosystem.

Game meat is a resource widely exploited by rural populations in various parts of the world. In recent decades, the growth in the number of people living near conserved areas has increased the demand for game meat. In this work, based on the Social-ecological Theory of Maximization, we seek to verify the influence of cost-benefit ratio, availability, and subjective preferences (flavor) in the selection of hunted species.

Global consumption and international trade in deforestation-associated commodities could influence malaria risk.

Deforestation can increase the transmission of malaria. Here, we build upon the existing link between malaria risk and deforestation by investigating how the global demand for commodities that increase deforestation can also increase malaria risk. We use a database of trade relationships to link the consumption of deforestation-implicated commodities in developed countries to estimates of country-level malaria risk in developing countries.

Vector competence, vectorial capacity of Nyssorhynchus darlingi and the basic reproduction number of Plasmodium vivax in agricultural settlements in the Amazonian Region of Brazil.

Background: Brazilian malaria control programmes successfully reduced the incidence and mortality rates from 2005 to 2016. Since 2017, increased malaria has been reported across the Amazon. Few field studies focus on the primary malaria vector in high to moderate endemic areas, Nyssorhynchus darlingi, as the key entomological component of malaria risk, and on the metrics of Plasmodium vivax propagation in Amazonian rural communities.

Exploring malaria vector diversity on the Amazon Frontier.

Background: Deforestation in the Amazon and the social vulnerability of its settler communities has been associated with increased malaria incidence. The feeding biology of the most important malaria vectors in the region, notably Nyssorhynchus darlingi, compounds efforts to control vectors and reduce transmission of what has become known as "Frontier Malaria". Exploring Anophelinae mosquito diversity is fundamental to understanding the species responsible for transmission and developing appropriate management and intervention strategies for malaria control in the Amazon River basin.

A method for estimating the deforestation timeline in rural settlements in a scenario of malaria transmission in frontier expansion in the Amazon Region.

The Malaria Frontier Hypothesis (MFH) is the current model for predicting malaria emergence in the Brazilian Amazon. It has two important dimensions, 'settlement time' and 'malaria incidence', and its prediction are: malaria incidence peaks five years after the initiation of human settlement and declines towards zero after an estimated 10 years. Although MFH is currently accepted, it has been challenged recently.

Abundance of impacted forest patches less than 5 km is a key driver of the incidence of malaria in Amazonian Brazil.

The precise role that deforestation for agricultural settlements and commercial forest products plays in promoting or inhibiting malaria incidence in Amazonian Brazil is controversial. Using publically available databases, we analyzed temporal malaria incidence (2009-2015) in municipalities of nine Amazonian states in relation to ecologically defined variables: (i) deforestation (rate of forest clearing over time); (ii) degraded forest (degree of human disturbance and openness of forest canopy for logging) and (iii) impacted forest (sum of deforested and degraded forest patches). We found that areas affected by one kilometer square of deforestation produced 27 new malaria cases (r² = 0.

Kerteszia Theobald (Diptera: Culicidae) mosquitoes and bromeliads: A landscape ecology approach regarding two species in the Atlantic rainforest.

On the ecological scale of an organism, a homogeneous geographical landscape can represent a mosaic of heterogeneous landscapes. The bionomy of Kerteszia mosquitoes can contribute to foundation landscape ecology by virtue of in the role of the configuration and composition of the habitat played in the distribution of mosquito species. Thus, this study aimed: to compare the abundance of Kerteszia in dense tropical rainforest, restinga and rural area, to assess the bioecological characteristics of the main bromeliads hosting Kerteszia, and to associate the bioecological arrangement of the bromeliads with Kerteszia distribution.

Economic impact of expanded use of biologic therapy for the treatment of rheumatoid arthritis and Crohn's disease in Argentina, Brazil, Colombia, and Mexico.

Objectives: To estimate economic impact resulting from increased biologics use for treatment of rheumatoid arthritis (RA) and Crohn's disease (CD) in Argentina, Brazil, Colombia, and Mexico.

Methods: The influence of increasing biologics use for treatment of RA during 2012-2022 and for treatment of CD during 2013-2023 was modeled from a societal perspective. The economic model incorporated current and projected medical, indirect, and drug costs and epidemiologic and economic factors.

[Public drinking water supply and egg laying by Aedes aegypti].

Objective: To evaluate the effect of the quality of publicly supplied water in domestic water tanks on egg laying by female Aedes aegypti.

Methods: Laboratory study on immature Ae. aegypti, collected from water-tanks in the municipality of Potim, SP, Southeastern Brazil.