Study Objective: To evaluate the efficacy, safety, and tolerability of extended-release divalproex sodium.
Design: Prospective, open-label, 4-week study
Setting: Long-term care facility of the Missouri Department of Mental Health.
Patients: Ten hospitalized patients (mean age 39.
In spring 2000, the Missouri Department of Mental Health mandated that its psychiatric inpatient facilities convert patients from trade-name to generic clozapine. The pharmacy department at our facility was encouraged to develop a conversion program to oversee and assess the efficacy and tolerability of the change. A protocol to monitor the conversion of patients to generic clozapine hospitalwide was developed.
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