A Comprehensive Review of Potential Warfarin-Fruit Interactions.

Purpose: The aim of this review is to discuss possible interactions that may occur between warfarin and fruit products.

Methods: A literature search was conducted using the search terms: “warfarin (Coumadin®) and fruit interactions, warfarin and fruit, warfarin and fruit juice, case reports and clinical trials”.

Results: A total of 23 citations (15 case reports and 7 controlled clinical trials) were reviewed.

A survey of community pharmacists and final-year student pharmacists and their perception of psychotherapeutic agents.

Introduction: The World Health Organization has estimated that as many as 450 million people worldwide have mental disorders. More than 44 million people in the United States have a mental disorder annually, estimating the annual direct costs of mental illness to exceed US$69 billion. Psychotherapeutic agents are used to treat mental illnesses and improve quality of life.

Detoxification from high-dose zolpidem using diazepam.

Objective: To report a rare case of physical and psychological addiction to an excessive dose of zolpidem and subsequent completed detoxification using diazepam.

Case Summary: A 46-year-old white man with a history of polysubstance abuse received a prescription for zolpidem 2 years prior to his hospital detoxification. During that time, he gradually escalated the total dosage to an amount of 400 mg/day in divided doses.