Publications by authors named "Leonard C Bailey"
Article Synopsis
- PCORnet is a National Research Network funded by PCORI that uses standardized electronic health records and patient input to facilitate pragmatic health research across 79 health system sites.
- The network has evolved to include additional data sources such as commercial health plans and federal insurance claims, enhancing its ability to represent patient health and experiences more comprehensively.
- With amendments allowing the inclusion of economic outcomes in research, PCORnet's phase 3, starting in January 2022, aims to bolster economic patient-centered outcomes through improved data linkages and stakeholder engagement.
Background: Approximately 50% of children with cancer in the United States who are aged <15 years receive primary treatment on a therapeutic clinical trial. To the authors' knowledge, it remains unknown whether trial enrollment has a clinical benefit compared with the best alternative standard therapy and/or off trial (ie, clinical trial effect). The authors conducted a retrospective matched cohort study to compare the morbidity and mortality of pediatric patients with cancer who are treated on a phase 3 clinical trial compared with those receiving standard therapy and/or off trial.
View Article and Find Full Text PDFThe United States Pharmacopeia recently published a general chapter specifically addressing on-ambulance storage of medications, including a suggestion for stock rotation. This study describes the effectiveness of a simple stock rotation strategy in mitigating EMS medication exposure to excessive heat and cold. Previously collected on-ambulance temperature data from 5 US cities were randomly resampled to generate model exposures of 2 days to 6 months duration.
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