Publications by authors named "Leona Knoke"
Background: Long-term neurological complaints after SARS-CoV-2 infection occur in 4-66% of children and adolescents. Controlled studies on the integrity of the peripheral nerve system are scarce. Therefore, we examined the somatosensory function in children and adolescents after SARS-CoV-2 infection in a case-control study compared with age-matched individuals.
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- - A study was conducted to investigate the long-term effects of both symptomatic and asymptomatic SARS-CoV-2 infections on lung function in children and adolescents, as little evidence existed on this topic prior to the research.
- - Researchers recruited 73 participants aged 5-18, who had previously tested positive for the virus, and assessed their pulmonary function through various tests while comparing them to 45 seronegative controls.
- - Among the infected participants, 27.1% reported ongoing symptoms, with only a small percentage experiencing respiratory issues, yet no significant differences in lung function were found between the SARS-CoV-2 cases and the control group.
Analysis of sweat chloride levels in cystic fibrosis (CF) patients is essential not only for diagnosis but also for the monitoring of therapeutic responses to new drugs, such as cystic fibrosis transmembrane conductance regulator (CFTR) modulators and potentiators. Using iontophoresis as the gold standard can cause complications like burns, is uncomfortable, and requires repetitive hospital visits, which can be particularly problematic during a pandemic, where distancing and hygiene requirements are increased; therefore, it is necessary to develop fast and simple measures for the diagnosis and monitoring of CF. A screen-printed, low-cost chloride sensor was developed to remotely monitor CF patients.
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