Purpose: The aim of this study was to assess the effectiveness of dorzolamide-timolol (DT) in the management of open-angle glaucoma (OAG) and ocular hypertension.
Methods: An open-label, 12-week, multicenter, Canadian study was conducted. Patients with untreated OAG or ocular hypertension received DT for 12 weeks to reduce intraocular pressure (IOP).
Objective: To study the morphology of the corneal endothelium in patients diagnosed with corneal guttata using an image processing algorithm based on a contour detection method.
Design: Retrospective observational case series.
Participants: Twenty-four subjects with known corneal guttata.
Purpose: To develop a semiautomatic method to analyze morphology of cells and guttae in corneal endothelium.
Methods: Specular endothelial pictures from 42 and 21 subjects with healthy and guttate corneas, respectively, were analyzed independently by two observers with cell contour-extracting routines. One observer also analyzed healthy endothelia with the Corner method (Bambi).
Purpose: Decentration of the ablation zone is an occasional complication of excimer laser refractive surgery. We describe a technique to recenter the ablation zone without changing the refractive status obtained by the first surgery.
Methods: Sixteen eyes of 14 patients had moderate or marked ablation decentration after previous excimer laser surgery for myopia, but with only minor residual refractive error.
Purpose: We describe a retreatment technique using a combination of large-diameter myopic and hyperopic excimer laser ablations of a near equivalent diopter value to enlarge previous small ablation zones without altering the refractive result obtained by the initial surgery.
Methods: Eight eyes of six patients were retreated with a Technolas Keracor 217 laser in order to enlarge the optical zone. All patients had a good refractive result after the initial surgery, but reported halos under low light conditions.