Publications by authors named "Leon Huynh"
Choroidal Changes in Rhesus Macaques in Aging and Age-Related Drusen.
Invest Ophthalmol Vis Sci
September 2023
Article Synopsis
- The study investigates choroidal thickness and vascularity in aged rhesus macaques to understand changes related to aging and age-related macular degeneration (AMD).
- Using optical coherence tomography, researchers analyzed 244 eyes from 122 macaques, measuring various parameters including choroidal thickness (CT) and choroidal vascularity index (CVI), and assessing the impact of soft drusen.
- Findings show that choroidal thickness and vascularity decrease with age, but eyes with soft drusen are thicker and more vascular, displaying similarities to pachydrusen seen in human AMD patients.
The small intestinal mucosa constitutes a physical barrier separating the gut lumen from sterile internal tissues. Junctional complexes between cells regulate transport across the barrier, preventing water loss and the entry of noxious molecules or pathogens. Inflammatory diseases in cattle disrupt this barrier; nonetheless, mechanisms of barrier disruption in cattle are poorly understood.
View Article and Find Full Text PDFIntroduction: Six to eight children are diagnosed with a malignant liver tumour yearly in the Netherlands. The majority of these tumours are hepatoblastoma (HB) and hepatocellular carcinoma (HCC), for which radical resection, often in combination with chemotherapy, is the only curative treatment option. We investigated the surgical outcome of children with a malignant liver tumour in a consecutive cohort in the Netherlands.
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