Publications by authors named "Leon Alexander Mclaren Berge"

Article Synopsis
  • The study investigates the link between asbestos exposure and pleural mesothelioma in Norwegian male offshore petroleum workers, finding 43 cases among 25,347 participants.
  • Using expert job-exposure matrices, the research indicates that increased asbestos exposure correlates with a higher risk of developing the cancer, particularly for those with prior exposure before offshore work.
  • No significant association was found between refractory ceramic fibres (RCFs) and pleural mesothelioma, reinforcing the focus on asbestos as a key risk factor.
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Purpose: Cutaneous melanoma is among the fastest growing malignancies in Norway and ultraviolet radiation (UVR) exposure is the primary environmental risk factor. Immunomodulating drugs can increase skin photosensitivity and suppress immune responses, and by such mechanisms influence melanoma risk. We, therefore, aimed to examine the associations between use of immunomodulating drugs and melanoma risk, at a nationwide population level.

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Purpose: Melanoma is the cancer with the most rapidly rising incidence rate in Norway. Although exposure to ultraviolet radiation (UVR) is the major environmental risk factor, other factors may also contribute. Antidepressants have cancer inhibiting and promoting side effects, and their prescription rates have increased in parallel with melanoma incidence.

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Introduction: The incidence of cutaneous melanoma (hereafter melanoma) has increased dramatically among fair-skinned populations worldwide. In Norway, melanoma is the most rapidly growing type of cancer, with a 47% increase among women and 57% among men in 2000-2016. Intermittent ultraviolet exposure early in life and phenotypic characteristics like a fair complexion, freckles and nevi are established risk factors, yet the aetiology of melanoma is multifactorial.

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