Publications by authors named "Leo Partouche"

Article Synopsis
  • - The study evaluated malnutrition prevalence in systemic sclerosis (SSc) patients at a referral center from 1985 to 2019, finding that 59.2% were malnourished and 25% had severe malnutrition.
  • - Malnutrition correlated with disease features, specifically cardiac involvement and limited mouth opening (interincisal distance <35 mm), indicating potential warning signs.
  • - The findings suggest that addressing malnutrition could be crucial for improving health outcomes in SSc patients, given its high prevalence and associations with serious disease symptoms.
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Cancer among patients with systemic sclerosis (SSc) would appear to be more prevalent than in the general population. Pathophysiological hypotheses are multiple, involving intertwined factors such as immune system antitumoral response, oxygen species dysregulation, and immunosuppressive treatments. We aimed to identify SSc patients with cancer monitored at our center, describing their clinical and immunological characteristics, such as cancer-specific outcomes.

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Systemic sclerosis (SSc) is an autoimmune connective tissue disorder, characterized by multisystem involvement, vasculopathy, and fibrosis. An increased risk of malignancy is observed in SSc (including breast and lung cancers), and in a subgroup of patients with specific autoantibodies (i.e.

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