Publications by authors named "Leo Gaasch"
Article Synopsis
- Cardiac implantable devices like CRT-Ds and CCMs are options for patients with heart failure and reduced left ventricular function despite medical treatment, but a direct comparison between the two has not been done before.* -
- The study analyzed data from two registries to compare 220 CRT-D patients and 105 CCM patients, finding that before treatment, CCM patients had worse heart function; however, both groups showed similar improvements after 12 months.* -
- Despite comparable functional improvements, CCM patients had significantly higher rates of heart failure hospitalizations (45.7% compared to 16.8% for CRT-D patients), indicating a potential downside to CCM therapy.*
Cardiac resynchronization therapy with implantable cardioverter defibrillators (CRT-Ds) are established therapy options for patients suffering from heart failure (HF). Several aspects of HF modification have yet to be described regarding etiology-dependent outcome differences in the long-term.The Mannheim CArdiac Resynchronization TherApy RetrospeCtive ObservAtioNAl (MARACANA) Registry retrospectively included all patients provided with CRTs in our center from 2013 to 2021.
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- Luxembourg's introduction of nirsevimab immunisation for RSV led to an impressive neonatal coverage of 84% in 2023.
- The number of paediatric RSV-related hospitalisations for infants under 6 months significantly decreased, dropping from 232 in 2022 to 72 in 2023.
- Additionally, hospital stays shortened and the average age of hospitalised children increased, indicating that nirsevimab effectively reduced severe RSV infections and lessened the burden on healthcare.
Background: Cardiac resynchronisation therapy (CRT) can be necessary in patients with chronic heart failure, who have already been provided with transvenous cardiac implantable electrical devices. Upgrade procedures revealed controversial results, while long-term outcomes regarding underlying Ischaemic- (ICM) or Non-Ischaemic heart disease (NICM) have yet to be described.
Methods: The Mannheim Cardiac Resynchronisation Therapy Registry (MARACANA) was designed as a retrospective observational single-centre registry, including all CRT implantations from 2013-2021 ( = 459).