Publications by authors named "Leo Foyle"
The extensive use of antibiotics in food animal production and disposal of untreated wastewater from food animal slaughter facilities may create a shift in microbiomes of different ecosystems by generating reservoirs of antimicrobial resistance along the human-animal-environmental interface. This epidemiological problem has been studied, but its magnitude and impact on a global scale is poorly characterised. A systematic review was done to determine global prevalence and distribution patterns of antimicrobial resistance in effluent wastewater from animal slaughter facilities.
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- An outbreak of neurological disease in grower pigs caused ataxia and paraparesis, showing signs of spinal cord damage weeks after weaning.
- Pathological findings revealed significant inflammation and neuron damage in the spinal cords, with molecular analysis identifying a virus related to porcine sapelovirus (PSV) as the likely culprit.
- This study marks the first confirmed case of polioencephalomyelitis in pigs due to a neuroinvasive PSV in the UK, with the virus showing high nucleotide homology to others in its family.