Publications by authors named "Leo A Bowsher"
Article Synopsis
- * The study explores the use of Raman spectroscopy as a fast and minimally invasive tool to detect Post-Translational Modifications (PTMs) and degradation in mAbs, specifically focusing on IgG4 molecules under various stress conditions.
- * Combining Raman with other techniques like PCA and circular dichroism, the researchers identified correlations between spectral peaks and specific PTMs or degradation levels, demonstrating Raman's potential as an in-line analytical tool during therapeutic production.
