Publications by authors named "Lenka Drasarova"

Familial dysautonomia is a debilitating congenital neurodegenerative disorder with no causative therapy. It is caused by a homozygous mutation in ELP1 gene, resulting in the production of the transcript lacking exon 20. The compounds studied as potential treatments include the clinical candidate kinetin, a plant hormone from the cytokinin family.

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Article Synopsis
  • Signals play a crucial role in the arbuscular mycorrhizal (AM) symbiosis between fungi and plants, with root-exuded strigolactones recognized as key early cues, while the involvement of other phytohormones like ethylene and cytokinins is less explored.
  • The study identified that an ethylene receptor, RiHHK6, in AM fungi can effectively sense ethylene signals and enhance spore germination in response to certain cytokinins, suggesting the fungi's adaptability to these hormonal cues.
  • The contrasting behavior of a candidate cytokinin receptor, RiHHK7, indicates that the perception of cytokinins might involve different receptors, highlighting the diverse roles of phytoh
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